| 1 | Fri Nov 11 | vs Old Dominion | W71-59 | 1-0 | 1.000 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 2 | Tue Nov 15 | vsPenn | L59-64 | 1-1 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 3 | Fri Nov 18 | vsTBD | W85-45 | 2-1 | .667 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 4 | Mon Nov 21 | vsUT Arlington | W59-38 | 3-1 | .750 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 5 | Tue Nov 22 | vsFGCU | L59-67 | 3-2 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 6 | Wed Nov 23 | atIndiana St | L81-85 | 3-3 | .500 | - | | Hulman Center · Terre Haute, IN |
| 7 | Sun Nov 27 | atTemple | L61-73 | 3-4 | .429 | - | | Liacouras Center · Philadelphia, PA |
| 8 | Wed Nov 30 | vsLafayette | W64-56 | 4-4 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 9 | Sat Dec 3 | vsPrinceton | L63-83 | 4-5 | .444 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 10 | Sat Dec 10 | atLa Salle | W65-58 (OT) | 5-5 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 11 | Wed Dec 14 | atSeton Hall | L49-66 | 5-6 | .455 | - | FS1 | Prudential Center · Newark, NJ |
| 12 | Sat Dec 17 | vsDelaware St | W85-52 | 6-6 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 14 | Thu Dec 29 | vsElon | W62-50 | 7-6 | .538 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 15 | Sat Dec 31 | vsWilliam & Mary | W66-56 | 8-6 | .571 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 16 | Thu Jan 5 | atTowson | L58-64 | 8-7 | .533 | - | CBSSN | SECU Arena · Towson, MD |
| 17 | Sat Jan 7 | vsMonmouth | W67-35 | 9-7 | .563 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 18 | Thu Jan 12 | atStony Brook | L66-67 | 9-8 | .529 | - | CBSSN | Island FCU Arena · Stony Brook, NY |
| 19 | Sat Jan 14 | atNortheastern | W76-55 | 10-8 | .556 | - | | Matthews Arena · Boston, MA |
| 20 | Thu Jan 19 | vsHampton | W79-73 | 11-8 | .579 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 21 | Sat Jan 21 | vsDelaware | W77-74 (OT) | 12-8 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 22 | Thu Jan 26 | atNC A&T | L55-68 | 12-9 | .571 | - | | Corbett Sports Center · Greensboro, NC |
| 23 | Sat Jan 28 | atElon | L58-72 | 12-10 | .545 | - | | Schar Center · Elon, NC |
| 24 | Thu Feb 2 | vsCharleston | W70-69 | 13-10 | .565 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 25 | Sat Feb 4 | atMonmouth | L67-69 | 13-11 | .542 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 26 | Wed Feb 8 | atDelaware | W58-54 | 14-11 | .560 | - | | Bob Carpenter Center · Newark, DE |
| 27 | Sat Feb 11 | vsTowson | W73-66 (OT) | 15-11 | .577 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 28 | Mon Feb 13 | atHofstra | L52-66 | 15-12 | .556 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 29 | Thu Feb 16 | vsUNC Wilmington | L71-72 (2OT) | 15-13 | .536 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 30 | Sat Feb 18 | atHampton | L72-75 | 15-14 | .517 | - | | Convocation Center (VA) · Hampton, VA |
| 31 | Thu Feb 23 | vsNortheastern | W75-48 | 16-14 | .533 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 32 | Sat Mar 4 | vsMonmouth | W64-45 | 17-14 | .548 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 33 | Sun Mar 5 | atUNC Wilmington | L68-73 | 17-15 | .531 | - | | Trask Coliseum · Wilmington, NC |
