| 1 | Tue Nov 7 | at La Salle | L61-67 | 0-1 | .000 | - | | Tom Gola Arena · Philadelphia, PA |
| 2 | Sat Nov 11 | at Winthrop | W74-72 | 1-1 | .500 | - | | Winthrop Coliseum · Rock Hill, SC |
| 3 | Tue Nov 14 | vs Temple | L64-66 | 1-2 | .333 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 4 | Fri Nov 17 | vs Fairfield | W65-47 | 2-2 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 5 | Sun Nov 19 | vs Queens | W62-52 | 3-2 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 6 | Sun Nov 26 | at Old Dominion | L61-68 (OT) | 3-3 | .500 | - | | Chartway Arena · Norfolk, VA |
| 7 | Wed Nov 29 | at Lafayette | W69-48 | 4-3 | .571 | - | | Kirby Sports Center · Easton, PA |
| 8 | Sat Dec 2 | at #18Villanova | W57-55 | 5-3 | .625 | - | | Finneran Pavilion · Villanova, PA |
| 9 | Tue Dec 5 | at Princeton | L70-81 | 5-4 | .556 | - | | Jadwin Gymnasium · Princeton, NJ |
| 10 | Sat Dec 9 | at West Virginia | L60-66 | 5-5 | .500 | - | | WVU Coliseum · Morgantown, WV |
| 11 | Sat Dec 16 | vs Albany | W71-52 | 6-5 | .545 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 12 | Mon Dec 18 | vs TBD | W117-49 | 7-5 | .583 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 13 | Fri Dec 22 | at Bryant | L86-104 | 7-6 | .538 | - | | Chace Athletic Center · Smithfield, RI |
| 14 | Mon Jan 1 | vs Hampton | W99-65 | 8-6 | .571 | - | CBS | Daskalakis Athletic Center · Philadelphia, PA |
| 15 | Thu Jan 4 | vs UNC Wilmington | W78-63 | 9-6 | .600 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 16 | Sat Jan 6 | at William & Mary | W77-55 | 10-6 | .625 | - | | Kaplan Arena · Williamsburg, VA |
| 17 | Thu Jan 11 | at NC A&T | W67-63 | 11-6 | .647 | - | | Corbett Sports Center · Greensboro, NC |
| 18 | Sat Jan 13 | at Elon | W89-69 | 12-6 | .667 | - | | Schar Center · Elon, NC |
| 19 | Thu Jan 18 | vs Monmouth | W78-74 | 13-6 | .684 | - | CBS | Daskalakis Athletic Center · Philadelphia, PA |
| 20 | Sat Jan 20 | vs Delaware | W86-67 | 14-6 | .700 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 21 | Thu Jan 25 | at Towson | L67-70 | 14-7 | .667 | - | | SECU Arena · Towson, MD |
| 22 | Sat Jan 27 | vsNC A&T | W62-47 | 15-7 | .682 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 23 | Thu Feb 1 | atMonmouth | L62-67 | 15-8 | .652 | - | | OceanFirst Bank Center · West Long Branch, NJ |
| 24 | Thu Feb 8 | atUNC Wilmington | L56-75 | 15-9 | .625 | - | | Trask Coliseum · Wilmington, NC |
| 25 | Sat Feb 10 | at Charleston | L70-80 | 15-10 | .600 | - | | TD Arena · Charleston, SC |
| 26 | Thu Feb 15 | vs Hofstra | W79-77 | 16-10 | .615 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 27 | Sat Feb 17 | vs Campbell | W81-66 | 17-10 | .630 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 28 | Thu Feb 22 | atHofstra | L57-69 | 17-11 | .607 | - | CBS | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 29 | Mon Feb 26 | atDelaware | W70-60 | 18-11 | .621 | - | CBS | Bob Carpenter Center · Newark, DE |
| 30 | Thu Feb 29 | vs Stony Brook | W90-86 | 19-11 | .633 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 31 | Sat Mar 2 | vs Northeastern | W73-59 | 20-11 | .645 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 32 | Sun Mar 10 | vsStony Brook | L88-91 (2OT) | 20-12 | .625 | - | | Daskalakis Athletic Center · Philadelphia, PA |
