| 1 | Tue Nov 9 | vs TBD | W103-74 | 1-0 | 1.000 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 2 | Fri Nov 12 | vsFairleigh | PPD | 15-14 | .517 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 3 | Sun Nov 14 | atSyracuse | L60-75 | 1-1 | .500 | - | ESPN2 | JMA Wireless Dome · Syracuse, NY |
| 4 | Wed Nov 17 | atSaint Joseph's | W78-75 | 2-1 | .667 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 5 | Mon Nov 22 | vsTulane | L87-90 (OT) | 2-2 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 6 | Tue Nov 23 | atCharlotte | W67-55 | 3-2 | .600 | - | | Dale F. Halton Arena · Charlotte, NC |
| 7 | Wed Nov 24 | atJ'Ville St | L64-72 | 3-3 | .500 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 8 | Thu Dec 2 | vsFairleigh | W86-65 | 4-3 | .571 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 9 | Sat Dec 4 | atPrinceton | L79-81 (OT) | 4-4 | .500 | - | | Jadwin Gymnasium · Princeton, NJ |
| 10 | Sat Dec 11 | atAbilene Chrstn | L56-73 | 4-5 | .444 | - | | Moody Coliseum (Abilene) · Abilene, TX |
| 11 | Tue Dec 14 | vsCoppin St | W76-69 | 5-5 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 14 | Wed Dec 29 | atCharleston | PPD | 15-14 | .517 | - | | TD Arena · Charleston, SC |
| 15 | Fri Dec 31 | atUNC Wilmington | PPD | 15-14 | .517 | - | | Trask Coliseum · Wilmington, NC |
| 16 | Mon Jan 3 | vsTowson | W65-61 | 6-5 | .545 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 17 | Tue Jan 11 | vsDelaware | L77-81 | 6-6 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 18 | Sat Jan 15 | atNortheastern | W76-68 | 7-6 | .538 | - | | Matthews Arena · Boston, MA |
| 19 | Mon Jan 17 | atHofstra | L68-71 | 7-7 | .500 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 20 | Thu Jan 20 | vsElon | W77-49 | 8-7 | .533 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 21 | Sat Jan 22 | vsWilliam & Mary | L75-83 | 8-8 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 22 | Thu Jan 27 | atJMU | W88-82 | 9-8 | .529 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 23 | Sat Jan 29 | atTowson | L62-66 | 9-9 | .500 | - | | SECU Arena · Towson, MD |
| 24 | Mon Jan 31 | atUNC Wilmington | L63-70 | 9-10 | .474 | - | | Trask Coliseum · Wilmington, NC |
| 25 | Thu Feb 3 | atDelaware | W76-68 | 10-10 | .500 | - | CBS | Bob Carpenter Center · Newark, DE |
| 26 | Mon Feb 7 | vsJMU | W72-66 | 11-10 | .524 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 27 | Thu Feb 10 | vsHofstra | L73-83 | 11-11 | .500 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 28 | Sat Feb 12 | vsNortheastern | W67-51 | 12-11 | .522 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 29 | Mon Feb 14 | atCharleston | L75-79 | 12-12 | .500 | - | | TD Arena · Charleston, SC |
| 30 | Thu Feb 17 | atWilliam & Mary | W72-57 | 13-12 | .520 | - | | Kaplan Arena · Williamsburg, VA |
| 31 | Sat Feb 19 | atElon | W71-60 | 14-12 | .538 | - | | Schar Center · Elon, NC |
| 32 | Thu Feb 24 | vsUNC Wilmington | L63-69 | 14-13 | .519 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 33 | Sat Feb 26 | vsCharleston | W80-79 | 15-13 | .536 | - | | Daskalakis Athletic Center · Philadelphia, PA |
| 34 | Sun Mar 6 | vsDelaware | L56-66 | 15-14 | .517 | - | | Daskalakis Athletic Center · Philadelphia, PA |
