| 1 | Mon Nov 7 | vs TBD | W85-58 | 1-0 | 1.000 | - | | Charles E. Smith Center · Washington, D.C. |
| 2 | Fri Nov 11 | vs Howard | W85-75 | 2-0 | 1.000 | - | | Charles E. Smith Center · Washington, D.C. |
| 3 | Mon Nov 14 | at Hofstra | L80-85 | 2-1 | .667 | - | | David S. Mack Sports and Exhibition Complex · Hempstead, NY |
| 4 | Fri Nov 18 | vs MD-Eastern | W69-64 | 3-1 | .750 | - | | Charles E. Smith Center · Washington, D.C. |
| 5 | Tue Nov 22 | vs UC San Diego | L70-75 | 3-2 | .600 | - | | Charles E. Smith Center · Washington, D.C. |
| 6 | Sat Nov 26 | vs New Hampshire | W75-54 | 4-2 | .667 | - | | Charles E. Smith Center · Washington, D.C. |
| 7 | Wed Nov 30 | vs South Carolina | W79-55 | 5-2 | .714 | - | CBS | Charles E. Smith Center · Washington, D.C. |
| 8 | Sun Dec 4 | at Radford | L76-86 | 5-3 | .625 | - | | Donald N. Dedmon Center · Radford, VA |
| 9 | Sat Dec 10 | vs American | L64-69 | 5-4 | .556 | - | | Charles E. Smith Center · Washington, D.C. |
| 10 | Tue Dec 13 | vs Coppin St | W83-71 | 6-4 | .600 | - | | Charles E. Smith Center · Washington, D.C. |
| 11 | Thu Dec 22 | at Washington St | L64-66 | 6-5 | .545 | - | ESPN2 | Friel Court at Beasley Coliseum · Pullman, WA |
| 12 | Fri Dec 23 | at Pepperdine | L70-81 | 6-6 | .500 | - | ESPN2 | Firestone Fieldhouse · Malibu, CA |
| 13 | Sun Dec 25 | vs Seattle U | L67-85 | 6-7 | .462 | - | ESPNU | Charles E. Smith Center · Washington, D.C. |
| 14 | Sat Dec 31 | at Loyola Chicago | W97-87 | 7-7 | .500 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 15 | Wed Jan 4 | at Richmond | L63-73 | 7-8 | .467 | - | | Robins Center · Richmond, VA |
| 16 | Sat Jan 7 | vs UMass | W81-73 | 8-8 | .500 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
| 17 | Sat Jan 14 | vs Saint Louis | L74-81 | 8-9 | .471 | - | | Charles E. Smith Center · Washington, D.C. |
| 18 | Mon Jan 16 | at George Mason | W78-75 | 9-9 | .500 | - | CBS | EagleBank Arena · Fairfax, VA |
| 19 | Sat Jan 21 | vs Dayton | W76-69 | 10-9 | .526 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
| 20 | Wed Jan 25 | vs Saint Joseph's | W92-91 (OT) | 11-9 | .550 | - | | Charles E. Smith Center · Washington, D.C. |
| 21 | Sat Jan 28 | at Fordham | L70-85 | 11-10 | .524 | - | | Rose Hill Gymnasium · Bronx, NY |
| 22 | Wed Feb 1 | at La Salle | L64-75 | 11-11 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 23 | Sat Feb 4 | vs Duquesne | L67-93 | 11-12 | .478 | - | | Charles E. Smith Center · Washington, D.C. |
| 24 | Wed Feb 8 | vsRichmond | W107-105 (2OT) | 12-12 | .500 | - | | Charles E. Smith Center · Washington, D.C. |
| 25 | Sat Feb 11 | atSaint Joseph's | L69-81 | 12-13 | .480 | - | | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 26 | Wed Feb 15 | vsGeorge Mason | L53-66 | 12-14 | .462 | - | | Charles E. Smith Center · Washington, D.C. |
| 27 | Sun Feb 19 | at St Bonaventure | W83-81 (OT) | 13-14 | .481 | - | USA Net | Reilly Center · Saint Bonaventure, NY |
| 28 | Wed Feb 22 | at Rhode Island | W89-80 (OT) | 14-14 | .500 | - | | Ryan Center · Kingston, RI |
| 29 | Sat Feb 25 | vsLa Salle | W92-85 | 15-14 | .517 | - | | Charles E. Smith Center · Washington, D.C. |
| 30 | Wed Mar 1 | at Davidson | W75-70 | 16-14 | .533 | - | | John M. Belk Arena · Davidson, NC |
| 31 | Sat Mar 4 | vs VCU | L68-74 | 16-15 | .516 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
| 32 | Wed Mar 8 | vsSaint Joseph's | L76-87 | 16-16 | .500 | - | USA Net | Charles E. Smith Center · Washington, D.C. |
