| 1 | Tue Nov 5 | at Towson | L58-72 | 0-1 | .000 | - | | SECU Arena · Towson, MD |
| 2 | Sat Nov 9 | vs Howard | W76-62 | 1-1 | .500 | - | | Charles E. Smith Center · Washington, D.C. |
| 3 | Tue Nov 12 | vs American | L65-67 | 1-2 | .333 | - | | Charles E. Smith Center · Washington, D.C. |
| 4 | Sat Nov 16 | vs Morgan St | L64-68 | 1-3 | .250 | - | | Charles E. Smith Center · Washington, D.C. |
| 5 | Fri Nov 22 | at Kansas City | L68-74 | 1-4 | .200 | - | | Swinney Recreation Center · Kansas City, MO |
| 6 | Sat Nov 23 | at Evansville | W78-70 | 2-4 | .333 | - | | Ford Center · Evansville, IN |
| 7 | Sun Nov 24 | at Milwaukee | W66-63 | 3-4 | .429 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 8 | Sun Dec 1 | at South Carolina | L65-74 | 3-5 | .375 | - | | Colonial Life Arena · Columbia, SC |
| 9 | Wed Dec 4 | vs Boston Univ | W64-63 | 4-5 | .444 | - | | Charles E. Smith Center · Washington, D.C. |
| 10 | Sat Dec 7 | vs Delaware | W66-56 | 5-5 | .500 | - | | Charles E. Smith Center · Washington, D.C. |
| 11 | Sat Dec 21 | vs Harvard | L75-88 | 5-6 | .455 | - | | Charles E. Smith Center · Washington, D.C. |
| 12 | Sat Dec 28 | vs Longwood | W78-65 | 6-6 | .500 | - | | Charles E. Smith Center · Washington, D.C. |
| 13 | Tue Dec 31 | at Vermont | L51-76 | 6-7 | .462 | - | | Patrick Gymnasium · Burlington, VT |
| 14 | Sun Jan 5 | vs St Bonaventure | L66-71 | 6-8 | .429 | - | | Charles E. Smith Center · Washington, D.C. |
| 15 | Wed Jan 8 | at Saint Louis | L58-63 | 6-9 | .400 | - | | Chaifetz Arena · St. Louis, MO |
| 16 | Sat Jan 11 | vs Duquesne | L61-66 | 6-10 | .375 | - | | Charles E. Smith Center · Washington, D.C. |
| 17 | Wed Jan 15 | vs George Mason | W73-67 | 7-10 | .412 | - | | Charles E. Smith Center · Washington, D.C. |
| 18 | Sat Jan 18 | at UMass | W75-51 | 8-10 | .444 | - | NBCSN | William D. Mullins Memorial Center · Amherst, MA |
| 19 | Wed Jan 22 | at Fordham | L54-59 | 8-11 | .421 | - | | Rose Hill Gymnasium · Bronx, NY |
| 20 | Sat Jan 25 | vs Saint Joseph's | W85-69 | 9-11 | .450 | - | | Charles E. Smith Center · Washington, D.C. |
| 21 | Wed Jan 29 | vs Davidson | W107-104 (4OT) | 10-11 | .476 | - | | Charles E. Smith Center · Washington, D.C. |
| 22 | Sat Feb 1 | at Richmond | L54-76 | 10-12 | .455 | - | | Robins Center · Richmond, VA |
| 23 | Wed Feb 5 | atSt Bonaventure | L47-72 | 10-13 | .435 | - | | Reilly Center · Saint Bonaventure, NY |
| 24 | Sat Feb 8 | vs Rhode Island | L51-82 | 10-14 | .417 | - | CBS | Charles E. Smith Center · Washington, D.C. |
| 25 | Sat Feb 15 | atGeorge Mason | W73-67 | 11-14 | .440 | - | CBS | EagleBank Arena · Fairfax, VA |
| 26 | Wed Feb 19 | atDuquesne | W70-67 | 12-14 | .462 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 27 | Sat Feb 22 | vs La Salle | L62-72 | 12-15 | .444 | - | | Charles E. Smith Center · Washington, D.C. |
| 28 | Wed Feb 26 | vsRichmond | L70-73 | 12-16 | .429 | - | | Charles E. Smith Center · Washington, D.C. |
| 29 | Sat Feb 29 | at VCU | L51-75 | 12-17 | .414 | - | CBS | Stuart C. Siegel Center · Richmond, VA |
| 30 | Wed Mar 4 | vsFordham | L52-63 | 12-18 | .400 | - | | Charles E. Smith Center · Washington, D.C. |
| 31 | Sat Mar 7 | at #3Dayton | L51-76 | 12-19 | .387 | - | | UD Arena · Dayton, OH |
| 32 | Wed Mar 11 | vsFordham | L52-72 | 12-20 | .375 | - | | Charles E. Smith Center · Washington, D.C. |
