| 1 | Tue Nov 5 | at #14Memphis | L64-97 | 0-1 | .000 | - | | FedExForum · Memphis, TN |
| 2 | Fri Nov 8 | vs TBD | W79-64 | 1-1 | .500 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 3 | Tue Nov 12 | at Liberty | L39-65 | 1-2 | .333 | - | | Liberty Arena · Lynchburg, VA |
| 4 | Mon Nov 18 | vsTBD | W103-79 | 2-2 | .500 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 5 | Fri Nov 22 | at Vanderbilt | L60-97 | 2-3 | .400 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 6 | Mon Nov 25 | at Austin Peay | L66-92 | 2-4 | .333 | - | | Winfield Dunn Center · Clarksville, TN |
| 7 | Wed Nov 27 | at Tulsa | L47-78 | 2-5 | .286 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 8 | Sat Dec 7 | vs Presbyterian | W80-68 | 3-5 | .375 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 9 | Wed Dec 11 | vs UNC Asheville | W90-85 (OT) | 4-5 | .444 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 10 | Wed Dec 18 | vs SC Upstate | L70-73 | 4-6 | .400 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 11 | Sat Dec 21 | at Charleston | L61-73 | 4-7 | .364 | - | | TD Arena · Charleston, SC |
| 12 | Mon Dec 30 | at Jacksonville | W58-52 | 5-7 | .417 | - | | Swisher Gymnasium · Jacksonville, FL |
| 13 | Sat Jan 4 | at Coppin St | W79-75 | 6-7 | .462 | - | | Physical Education Complex · Baltimore, MD |
| 14 | Mon Jan 6 | at Morgan St | L63-77 | 6-8 | .429 | - | | Hill Field House · Baltimore, MD |
| 15 | Mon Jan 13 | at Howard | W101-95 (OT) | 7-8 | .467 | - | | Burr Gymnasium · Washington, D.C. |
| 16 | Sat Jan 18 | vs FAMU | W81-65 | 8-8 | .500 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 17 | Mon Jan 20 | vs MD-Eastern | W68-53 | 9-8 | .529 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 18 | Sat Jan 25 | at Norfolk St | L62-73 | 9-9 | .500 | - | | Joseph G. Echols Hall · Norfolk, VA |
| 19 | Mon Jan 27 | vs Bethune | L74-78 | 9-10 | .474 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 20 | Sat Feb 1 | at NC Central | L56-73 | 9-11 | .450 | - | | McDougald-McLendon Arena · Durham, NC |
| 21 | Mon Feb 3 | at NC A&T | L63-78 | 9-12 | .429 | - | | Corbett Sports Center · Greensboro, NC |
| 22 | Mon Feb 10 | vs Delaware St | W100-86 | 10-12 | .455 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 23 | Sat Feb 15 | vsCoppin St | W70-66 | 11-12 | .478 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 24 | Mon Feb 17 | vsMorgan St | L72-78 | 11-13 | .458 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 25 | Sat Feb 22 | atBethune | L65-69 (OT) | 11-14 | .440 | - | | Moore Gymnasium (FL) · Daytona Beach, FL |
| 26 | Mon Feb 24 | atFAMU | L56-62 | 11-15 | .423 | - | | Al Lawson Center · Tallahassee, FL |
| 27 | Sat Feb 29 | vsNC Central | L82-83 (2OT) | 11-16 | .407 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 28 | Mon Mar 2 | vsNC A&T | L65-76 | 11-17 | .393 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 29 | Tue Mar 10 | vsHoward | L63-70 | 11-18 | .379 | - | | S-H-M Memorial Center · Orangeburg, SC |
