| 1 | Mon Nov 6 | at Cincinnati | L58-69 | 0-1 | .000 | - | | Fifth Third Arena · Cincinnati, OH |
| 2 | Fri Nov 10 | vs Little Rock | W86-71 | 1-1 | .500 | - | | Credit Union 1 Arena · Chicago, IL |
| 3 | Tue Nov 14 | at Loyola Chicago | W72-67 | 2-1 | .667 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 4 | Sun Nov 19 | vs TBD | W99-48 | 3-1 | .750 | - | | Credit Union 1 Arena · Chicago, IL |
| 5 | Fri Nov 24 | at MTSU | W70-40 | 4-1 | .800 | - | | Murphy Center · Murfreesboro, TN |
| 6 | Sat Nov 25 | vs G Washington | W89-79 | 5-1 | .833 | - | | Credit Union 1 Arena · Chicago, IL |
| 7 | Sun Nov 26 | at UNC Greensboro | L57-58 | 5-2 | .714 | - | | Greensboro Coliseum · Greensboro, NC |
| 8 | Thu Nov 30 | vs Illinois St | L64-69 | 5-3 | .625 | - | | Credit Union 1 Arena · Chicago, IL |
| 9 | Fri Dec 8 | at J'Ville St | W55-49 | 6-3 | .667 | - | | Pete Mathews Coliseum · Jacksonville, AL |
| 10 | Tue Dec 12 | vs Green Bay | L68-70 | 6-4 | .600 | - | | Credit Union 1 Arena · Chicago, IL |
| 11 | Sat Dec 16 | vs W Michigan | W89-68 | 7-4 | .636 | - | | Credit Union 1 Arena · Chicago, IL |
| 12 | Thu Dec 21 | vs Incarnate Word | L66-67 | 7-5 | .583 | - | | Credit Union 1 Arena · Chicago, IL |
| 13 | Sat Dec 30 | at S Illinois | L50-62 | 7-6 | .538 | - | | Banterra Center · Carbondale, IL |
| 14 | Tue Jan 2 | at Murray St | L73-85 | 7-7 | .500 | - | | CFSB Center · Murray, KY |
| 15 | Sat Jan 6 | vs Valparaiso | W70-64 | 8-7 | .533 | - | | Credit Union 1 Arena · Chicago, IL |
| 16 | Wed Jan 10 | at Northern Iowa | L59-67 | 8-8 | .500 | - | | McLeod Center · Cedar Falls, IA |
| 17 | Sat Jan 13 | vs Bradley | L59-77 | 8-9 | .471 | - | | Credit Union 1 Arena · Chicago, IL |
| 18 | Wed Jan 17 | vsMurray St | L58-73 | 8-10 | .444 | - | | Credit Union 1 Arena · Chicago, IL |
| 19 | Sat Jan 20 | atValparaiso | L77-84 | 8-11 | .421 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 20 | Wed Jan 24 | vs Indiana St | L83-89 | 8-12 | .400 | - | | Credit Union 1 Arena · Chicago, IL |
| 21 | Sat Jan 27 | at Belmont | L65-74 | 8-13 | .381 | - | | Curb Event Center Arena · Nashville, TN |
| 22 | Wed Jan 31 | at Evansville | L60-77 | 8-14 | .364 | - | | Ford Center · Evansville, IN |
| 23 | Sat Feb 3 | vsS Illinois | L71-74 | 8-15 | .348 | - | | Credit Union 1 Arena · Chicago, IL |
| 24 | Wed Feb 7 | atIllinois St | W61-56 | 9-15 | .375 | - | | Redbird Arena · Normal, IL |
| 25 | Sun Feb 11 | vsNorthern Iowa | W71-65 | 10-15 | .400 | - | | Credit Union 1 Arena · Chicago, IL |
| 26 | Wed Feb 14 | atBradley | L73-85 | 10-16 | .385 | - | | Carver Arena · Peoria, IL |
| 27 | Sun Feb 18 | vsBelmont | L60-75 | 10-17 | .370 | - | | Credit Union 1 Arena · Chicago, IL |
| 28 | Wed Feb 21 | vsEvansville | W88-79 | 11-17 | .393 | - | | Credit Union 1 Arena · Chicago, IL |
| 29 | Sat Feb 24 | atIndiana St | L73-88 | 11-18 | .379 | - | | Hulman Center · Terre Haute, IN |
| 30 | Wed Feb 28 | vs Drake | L105-107 (3OT) | 11-19 | .367 | - | | Credit Union 1 Arena · Chicago, IL |
| 31 | Sun Mar 3 | at Missouri St | L59-69 | 11-20 | .355 | - | | Great Southern Bank Arena · Springfield, MO |
| 32 | Thu Mar 7 | atS Illinois | W84-82 (2OT) | 12-20 | .375 | - | | Banterra Center · Carbondale, IL |
| 33 | Fri Mar 8 | atBradley | L47-74 | 12-21 | .364 | - | | Carver Arena · Peoria, IL |
