| 1 | Tue Nov 9 | at Dayton | L54-64 | 0-1 | .000 | - | | UD Arena · Dayton, OH |
| 2 | Sat Nov 13 | at Valparaiso | W74-70 (OT) | 1-1 | .500 | - | | Athletics-Recreation Center · Valparaiso, IN |
| 3 | Tue Nov 16 | vs TBD | W91-50 | 2-1 | .667 | - | | Credit Union 1 Arena · Chicago, IL |
| 4 | Sat Nov 20 | at Loyola Chicago | L63-80 | 2-2 | .500 | - | | Joseph J. Gentile Arena · Chicago, IL |
| 5 | Thu Nov 25 | at Hawai'i | L80-88 | 2-3 | .400 | - | | Stan Sheriff Center · Honolulu, HI |
| 6 | Fri Nov 26 | at San Diego | L52-64 | 2-4 | .333 | - | | Jenny Craig Pavilion · San Diego, CA |
| 7 | Thu Dec 2 | vs Oakland | L77-81 | 2-5 | .286 | - | | Credit Union 1 Arena · Chicago, IL |
| 8 | Sun Dec 5 | vs Detroit Mercy | L56-64 | 2-6 | .250 | - | | Credit Union 1 Arena · Chicago, IL |
| 9 | Sat Dec 11 | at C Michigan | W71-67 | 3-6 | .333 | - | | McGuirk Arena · Mount Pleasant, MI |
| 10 | Tue Dec 14 | vs DePaul | L66-72 | 3-7 | .300 | - | | Credit Union 1 Arena · Chicago, IL |
| 11 | Sun Dec 19 | vs N Illinois | W61-60 | 4-7 | .364 | - | | Credit Union 1 Arena · Chicago, IL |
| 13 | Thu Jan 6 | at Wright St | L72-90 | 4-8 | .333 | - | | Nutter Center · Dayton, OH |
| 15 | Mon Jan 10 | at IU Indy | W67-65 | 5-8 | .385 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 16 | Thu Jan 13 | at Milwaukee | W81-77 | 6-8 | .429 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 17 | Sat Jan 15 | at Green Bay | W80-63 | 7-8 | .467 | - | | Resch Center · Ashwaubenon, WI |
| 18 | Thu Jan 20 | vs N Kentucky | L70-74 (OT) | 7-9 | .438 | - | | Credit Union 1 Arena · Chicago, IL |
| 19 | Sat Jan 22 | vsWright St | L81-97 | 7-10 | .412 | - | | Credit Union 1 Arena · Chicago, IL |
| 20 | Thu Jan 27 | atDetroit Mercy | L67-80 | 7-11 | .389 | - | | Calihan Hall · Detroit, MI |
| 21 | Sat Jan 29 | atOakland | L74-81 | 7-12 | .368 | - | | Athletics Center O'rena · Rochester, MI |
| 22 | Thu Feb 3 | vs Robert Morris | W80-75 | 8-12 | .400 | - | | Credit Union 1 Arena · Chicago, IL |
| 23 | Sat Feb 5 | vs Youngstown St | L64-66 | 8-13 | .381 | - | | Credit Union 1 Arena · Chicago, IL |
| 24 | Thu Feb 10 | at Cleveland St | W76-75 | 9-13 | .409 | - | | Wolstein Center · Cleveland, OH |
| 25 | Sat Feb 12 | at Purdue FW | L66-73 | 9-14 | .391 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 26 | Mon Feb 14 | vsIU Indy | W57-54 | 10-14 | .417 | - | | Credit Union 1 Arena · Chicago, IL |
| 27 | Thu Feb 17 | atYoungstown St | L79-88 | 10-15 | .400 | - | | Beeghly Center · Youngstown, OH |
| 28 | Sat Feb 19 | atRobert Morris | W96-88 (OT) | 11-15 | .423 | - | | UPMC Events Center · Moon Township, PA |
| 29 | Thu Feb 24 | vsGreen Bay | W81-77 | 12-15 | .444 | - | | Credit Union 1 Arena · Chicago, IL |
| 30 | Sat Feb 26 | vsMilwaukee | W71-58 | 13-15 | .464 | - | | Credit Union 1 Arena · Chicago, IL |
| 31 | Tue Mar 1 | atMilwaukee | W80-69 | 14-15 | .483 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 32 | Thu Mar 3 | atPurdue FW | L72-78 | 14-16 | .467 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
