| 1 | Wed Nov 25 | at N Illinois | W65-61 | 1-0 | 1.000 | - | | NIU Convocation Center · Dekalb, IL |
| 2 | Sat Nov 28 | vsC Michigan | W74-72 | 2-0 | 1.000 | - | | Credit Union 1 Arena · Chicago, IL |
| 3 | Tue Dec 1 | vsValparaiso | W66-50 | 3-0 | 1.000 | - | | Credit Union 1 Arena · Chicago, IL |
| 4 | Sat Dec 5 | atBall State | L66-68 | 3-1 | .750 | - | | Worthen Arena · Muncie, IN |
| 5 | Sun Dec 13 | vsLoyola Chicago | L66-77 | 3-2 | .600 | - | | Credit Union 1 Arena · Chicago, IL |
| 6 | Sat Dec 19 | vsOakland | W74-72 | 4-2 | .667 | - | | Credit Union 1 Arena · Chicago, IL |
| 7 | Sun Dec 20 | vsOakland | W90-73 | 5-2 | .714 | - | | Credit Union 1 Arena · Chicago, IL |
| 12 | Fri Jan 8 | atPurdue FW | L89-96 (OT) | 5-3 | .625 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 13 | Sat Jan 9 | atPurdue FW | L55-88 | 5-4 | .556 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 14 | Fri Jan 15 | vsRobert Morris | W67-53 | 6-4 | .600 | - | | Credit Union 1 Arena · Chicago, IL |
| 15 | Sat Jan 16 | vsRobert Morris | W66-62 (OT) | 7-4 | .636 | - | | Credit Union 1 Arena · Chicago, IL |
| 16 | Fri Jan 22 | atYoungstown St | W67-66 | 8-4 | .667 | - | | Beeghly Center · Youngstown, OH |
| 17 | Sat Jan 23 | atYoungstown St | L77-85 | 8-5 | .615 | - | | Beeghly Center · Youngstown, OH |
| 18 | Fri Jan 29 | atN Kentucky | L68-72 | 8-6 | .571 | - | | Truist Arena · Highland Heights, KY |
| 19 | Sat Jan 30 | atN Kentucky | L67-69 | 8-7 | .533 | - | | Truist Arena · Highland Heights, KY |
| 20 | Fri Feb 5 | vsWright St | L47-72 | 8-8 | .500 | - | | Credit Union 1 Arena · Chicago, IL |
| 21 | Sat Feb 6 | vsWright St | L57-77 | 8-9 | .471 | - | | Credit Union 1 Arena · Chicago, IL |
| 22 | Fri Feb 12 | atIU Indy | L69-89 | 8-10 | .444 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 23 | Sat Feb 13 | atIU Indy | L81-88 | 8-11 | .421 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 24 | Fri Feb 19 | vsGreen Bay | W61-58 | 9-11 | .450 | - | | Credit Union 1 Arena · Chicago, IL |
| 25 | Sat Feb 20 | vsGreen Bay | L59-69 | 9-12 | .429 | - | | Credit Union 1 Arena · Chicago, IL |
| 26 | Thu Feb 25 | atYoungstown St | L58-74 | 9-13 | .409 | - | | Beeghly Center · Youngstown, OH |
