| 1 | Tue Nov 9 | vs Utah Tech | W97-63 | 1-0 | 1.000 | #1 | | McCarthey Athletic Center · Spokane, WA |
| 2 | Sat Nov 13 | vs #5Texas | W86-74 | 2-0 | 1.000 | #1 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 3 | Mon Nov 15 | vs Alcorn St | W84-57 | 3-0 | 1.000 | #1 | | McCarthey Athletic Center · Spokane, WA |
| 4 | Fri Nov 19 | vs Bellarmine | W92-50 | 4-0 | 1.000 | #1 | | McCarthey Athletic Center · Spokane, WA |
| 5 | Mon Nov 22 | at C Michigan | W107-54 | 5-0 | 1.000 | - | ESPNU | McGuirk Arena · Mount Pleasant, MI |
| 6 | Tue Nov 23 | at UCLA | W83-63 | 6-0 | 1.000 | - | ESPN | Pauley Pavilion · Los Angeles, CA |
| 7 | Fri Nov 26 | at Duke | L81-84 | 6-1 | .857 | - | ESPN | Cameron Indoor Stadium · Durham, NC |
| 8 | Mon Nov 29 | vs Tarleton | W64-55 | 7-1 | .875 | #3 | | McCarthey Athletic Center · Spokane, WA |
| 9 | Sat Dec 4 | vs Alabama | L82-91 | 7-2 | .778 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 10 | Thu Dec 9 | vs Merrimack | W80-55 | 8-2 | .800 | #5 | | McCarthey Athletic Center · Spokane, WA |
| 12 | Sat Dec 18 | vs Texas Tech | W69-55 | 9-2 | .818 | - | CBS | McCarthey Athletic Center · Spokane, WA |
| 13 | Mon Dec 20 | vs N Arizona | W95-49 | 10-2 | .833 | #4 | | McCarthey Athletic Center · Spokane, WA |
| 14 | Tue Dec 28 | vs North Alabama | W93-63 | 11-2 | .846 | #4 | | McCarthey Athletic Center · Spokane, WA |
| 15 | Thu Dec 30 | at San Diego | PPD | 28-4 | .875 | #4 | | Jenny Craig Pavilion · San Diego, CA |
| 17 | Sat Jan 8 | vs Pepperdine | W117-83 | 12-2 | .857 | #4 | | McCarthey Athletic Center · Spokane, WA |
| 18 | Thu Jan 13 | vs BYU | W110-84 | 13-2 | .867 | #2 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 19 | Sat Jan 15 | at Santa Clara | W115-83 | 14-2 | .875 | #2 | | Leavey Center · Santa Clara, CA |
| 20 | Thu Jan 20 | vs San Francisco | W78-62 | 15-2 | .882 | #1 | CBS | McCarthey Athletic Center · Spokane, WA |
| 21 | Thu Jan 27 | vs LMU | W89-55 | 16-2 | .889 | #2 | CBS | McCarthey Athletic Center · Spokane, WA |
| 22 | Sat Jan 29 | vs Portland | W104-72 | 17-2 | .895 | #2 | | McCarthey Athletic Center · Spokane, WA |
| 23 | Thu Feb 3 | atSan Diego | W92-62 | 18-2 | .900 | #2 | ESPN2 | Jenny Craig Pavilion · San Diego, CA |
| 24 | Sat Feb 5 | atBYU | W90-57 | 19-2 | .905 | #2 | ESPN | Marriott Center · Provo, UT |
| 25 | Thu Feb 10 | vs Pacific | W89-51 | 20-2 | .909 | #2 | CBS | McCarthey Athletic Center · Spokane, WA |
| 26 | Sat Feb 12 | vs #22Saint Mary's | W74-58 | 21-2 | .913 | #2 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 27 | Wed Feb 16 | atPepperdine | W86-66 | 22-2 | .917 | #1 | ESPN2 | Firestone Fieldhouse · Malibu, CA |
| 28 | Sat Feb 19 | vsSanta Clara | W81-69 | 23-2 | .920 | #1 | | McCarthey Athletic Center · Spokane, WA |
| 29 | Thu Feb 24 | atSan Francisco | W89-73 | 24-2 | .923 | #1 | ESPN2 | War Memorial at the Sobrato Center · San Francisco, CA |
| 30 | Sat Feb 26 | at#23Saint Mary's | L57-67 | 24-3 | .889 | #1 | ESPN | University Credit Union Pavilion · Moraga, CA |
| 31 | Mon Mar 7 | vsSan Francisco | W81-71 | 25-3 | .893 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 32 | Tue Mar 8 | vsSaint Mary's | W82-69 | 26-3 | .897 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 33 | Thu Mar 17 | vs #16Georgia St | W93-72 | 27-3 | .900 | #1 | TNT | McCarthey Athletic Center · Spokane, WA |
| 34 | Sat Mar 19 | vs #9Memphis | W82-78 | 28-3 | .903 | #1 | TBS | McCarthey Athletic Center · Spokane, WA |
| 35 | Thu Mar 24 | vs #4Arkansas | L68-74 | 28-4 | .875 | #1 | CBS | McCarthey Athletic Center · Spokane, WA |
Washington