| 1 | Mon Nov 7 | vs North Florida | W104-63 | 1-0 | 1.000 | #2 | | McCarthey Athletic Center · Spokane, WA |
| 2 | Fri Nov 11 | vsMichigan St | W64-63 | 2-0 | 1.000 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 3 | Wed Nov 16 | at#11Texas | L74-93 | 2-1 | .667 | #2 | ESPN2 | Moody Center · Austin, TX |
| 4 | Sun Nov 20 | vs#4Kentucky | W88-72 | 3-1 | .750 | #2 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 5 | Fri Nov 25 | vsPortland St | W102-78 | 4-1 | .800 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 6 | Fri Nov 25 | vsPurdue | L66-84 | 4-2 | .667 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 7 | Sun Nov 27 | vsXavier | W88-84 | 5-2 | .714 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 8 | Fri Dec 2 | vs#6Baylor | L63-64 | 5-3 | .625 | #14 | | McCarthey Athletic Center · Spokane, WA |
| 9 | Mon Dec 5 | vsKent State | W73-66 | 6-3 | .667 | #18 | | McCarthey Athletic Center · Spokane, WA |
| 10 | Fri Dec 9 | vsWashington | W77-60 | 7-3 | .700 | #18 | | McCarthey Athletic Center · Spokane, WA |
| 11 | Mon Dec 12 | vsN Illinois | W88-67 | 8-3 | .727 | #15 | | McCarthey Athletic Center · Spokane, WA |
| 12 | Sat Dec 17 | atAlabama | W100-90 | 9-3 | .750 | - | CBS | Coleman Coliseum · Tuscaloosa, AL |
| 13 | Tue Dec 20 | vsMontana | W85-75 | 10-3 | .769 | #11 | | McCarthey Athletic Center · Spokane, WA |
| 14 | Wed Dec 28 | vsTBD | W120-42 | 11-3 | .786 | #10 | | McCarthey Athletic Center · Spokane, WA |
| 15 | Sat Dec 31 | vsPepperdine | W111-88 | 12-3 | .800 | #10 | | McCarthey Athletic Center · Spokane, WA |
| 16 | Thu Jan 5 | atSan Francisco | W77-75 | 13-3 | .813 | #9 | ESPN2 | War Memorial at the Sobrato Center · San Francisco, CA |
| 17 | Sat Jan 7 | atSanta Clara | W81-76 | 14-3 | .824 | #9 | | Leavey Center · Santa Clara, CA |
| 18 | Thu Jan 12 | atBYU | W75-74 | 15-3 | .833 | #8 | ESPN | Marriott Center · Provo, UT |
| 19 | Sat Jan 14 | vsPortland | W115-75 | 16-3 | .842 | #8 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 20 | Thu Jan 19 | vsLMU | L67-68 | 16-4 | .800 | #6 | | McCarthey Athletic Center · Spokane, WA |
| 21 | Sat Jan 21 | atPacific | W99-90 | 17-4 | .810 | #6 | | Alex G. Spanos Center · Stockton, CA |
| 22 | Sat Jan 28 | atPortland | W82-67 | 18-4 | .818 | #14 | | Chiles Center · Portland, OR |
| 23 | Thu Feb 2 | vsSanta Clara | W88-70 | 19-4 | .826 | #12 | CBS | McCarthey Athletic Center · Spokane, WA |
| 24 | Sat Feb 4 | at#18Saint Mary's | L70-78 (OT) | 19-5 | .792 | #12 | ESPN | University Credit Union Pavilion · Moraga, CA |
| 25 | Thu Feb 9 | vsSan Francisco | W99-81 | 20-5 | .800 | #16 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 26 | Sat Feb 11 | vsBYU | W88-81 | 21-5 | .808 | #16 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 27 | Thu Feb 16 | atLMU | W108-65 | 22-5 | .815 | #13 | CBS | Gersten Pavilion · Los Angeles, CA |
| 28 | Sat Feb 18 | atPepperdine | W97-88 | 23-5 | .821 | #13 | | Firestone Fieldhouse · Malibu, CA |
| 29 | Thu Feb 23 | vsSan Diego | W97-72 | 24-5 | .828 | #12 | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 30 | Sat Feb 25 | vs#15Saint Mary's | W77-68 | 25-5 | .833 | #12 | ESPN | McCarthey Athletic Center · Spokane, WA |
| 31 | Wed Mar 1 | vsChicago St | W104-65 | 26-5 | .839 | #10 | | McCarthey Athletic Center · Spokane, WA |
| 32 | Mon Mar 6 | vsSan Francisco | W84-73 | 27-5 | .844 | - | ESPN2 | McCarthey Athletic Center · Spokane, WA |
| 33 | Tue Mar 7 | atSaint Mary's | W77-51 | 28-5 | .848 | - | ESPN | University Credit Union Pavilion · Moraga, CA |
| 34 | Fri Mar 17 | vs#14Grand Canyon | W82-70 | 29-5 | .853 | #3 | truTV | McCarthey Athletic Center · Spokane, WA |
| 35 | Sun Mar 19 | vs#6TCU | W84-81 | 30-5 | .857 | #3 | TBS | McCarthey Athletic Center · Spokane, WA |
| 36 | Thu Mar 23 | at#2UCLA | W79-76 | 31-5 | .861 | #3 | CBS | Pauley Pavilion · Los Angeles, CA |
| 37 | Sat Mar 25 | vs#4UConn | L54-82 | 31-6 | .838 | #3 | TBS | McCarthey Athletic Center · Spokane, WA |
