| 1 | Tue Nov 5 | vs William & Mary | L56-70 | 0-1 | .000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 2 | Sat Nov 9 | at Wofford | L61-89 | 0-2 | .000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 3 | Wed Nov 13 | at Boston College | L33-59 | 0-3 | .000 | - | | Silvio O. Conte Forum · Chestnut Hill, MA |
| 4 | Mon Nov 18 | at Belmont | L51-90 | 0-4 | .000 | - | | Curb Event Center Arena · Nashville, TN |
| 5 | Wed Nov 20 | at Saint Louis | L55-67 | 0-5 | .000 | - | | Chaifetz Arena · St. Louis, MO |
| 6 | Sat Nov 23 | vs E Washington | L74-90 | 0-6 | .000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 7 | Tue Nov 26 | vs TBD | W90-73 | 1-6 | .143 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 8 | Mon Dec 2 | at North Florida | L70-93 | 1-7 | .125 | - | | UNF Arena · Jacksonville, FL |
| 9 | Thu Dec 5 | vs Elon | W70-66 (OT) | 2-7 | .222 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 10 | Sat Dec 14 | at FAU | L64-81 | 2-8 | .200 | - | | FAU Arena · Boca Raton, FL |
| 11 | Wed Dec 18 | vs Valparaiso | L72-87 | 2-9 | .182 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 12 | Sat Dec 21 | vsTBD | W92-66 | 3-9 | .250 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 13 | Mon Dec 30 | at Texas | L58-89 | 3-10 | .231 | - | LHN | Moody Center · Austin, TX |
| 14 | Sat Jan 4 | at Radford | L62-73 | 3-11 | .214 | - | | Donald N. Dedmon Center · Radford, VA |
| 15 | Wed Jan 8 | vs Winthrop | L57-79 | 3-12 | .200 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 16 | Sat Jan 11 | at Presbyterian | L62-77 | 3-13 | .188 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 17 | Thu Jan 16 | at UNC Asheville | W68-66 | 4-13 | .235 | - | | Kimmel Arena · Asheville, NC |
| 18 | Sat Jan 18 | vs Charleston So | L60-79 | 4-14 | .222 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 19 | Mon Jan 20 | at SC Upstate | W70-62 | 5-14 | .263 | - | | G.B. Hodge Center · Spartanburg, SC |
| 20 | Thu Jan 23 | vs Gardner-Webb | L76-79 (OT) | 5-15 | .250 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 21 | Sat Jan 25 | vs Longwood | L62-72 | 5-16 | .238 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 22 | Thu Jan 30 | at Campbell | W62-57 | 6-16 | .273 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 23 | Thu Feb 6 | vs Hampton | W88-85 | 7-16 | .304 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 24 | Sat Feb 8 | vsRadford | L70-81 | 7-17 | .292 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 25 | Mon Feb 10 | atGardner-Webb | L55-86 | 7-18 | .280 | - | | Paul Porter Arena · Boiling Springs, NC |
| 26 | Thu Feb 13 | atCharleston So | L63-66 | 7-19 | .269 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 27 | Sat Feb 15 | vsSC Upstate | W62-54 | 8-19 | .296 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 28 | Thu Feb 20 | vsPresbyterian | W82-70 | 9-19 | .321 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 29 | Sat Feb 22 | atLongwood | L54-57 | 9-20 | .310 | - | | Willett Hall · Farmville, VA |
| 30 | Thu Feb 27 | vsUNC Asheville | L76-80 | 9-21 | .300 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 31 | Sat Feb 29 | atWinthrop | L76-84 | 9-22 | .290 | - | | Winthrop Coliseum · Rock Hill, SC |
| 32 | Tue Mar 3 | atSC Upstate | L59-69 | 9-23 | .281 | - | | G.B. Hodge Center · Spartanburg, SC |
