| 1 | Tue Nov 9 | vs TBD | W108-59 | 1-0 | 1.000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 2 | Fri Nov 12 | at Northwestern | L60-95 | 1-1 | .500 | - | | Welsh-Ryan Arena · Evanston, IL |
| 3 | Tue Nov 16 | at Notre Dame | L61-70 | 1-2 | .333 | - | ACC Network | Purcell Pavilion · South Bend, IN |
| 4 | Sat Nov 20 | vs Howard | W73-63 | 2-2 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 5 | Sun Nov 21 | vs Georgia St | L66-74 (OT) | 2-3 | .400 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 6 | Sat Nov 27 | vsTBD | W90-60 | 3-3 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 7 | Tue Nov 30 | vs Furman | L70-74 (2OT) | 3-4 | .429 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 8 | Sat Dec 4 | at Elon | W83-77 | 4-4 | .500 | - | | Schar Center · Elon, NC |
| 9 | Tue Dec 7 | vsTBD | W64-59 | 5-4 | .556 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 10 | Fri Dec 10 | at SC State | L66-67 | 5-5 | .500 | - | | S-H-M Memorial Center · Orangeburg, SC |
| 11 | Sat Dec 18 | vs UNC Wilmington | L69-71 (OT) | 5-6 | .455 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 12 | Tue Dec 21 | vs FAU | W55-52 | 6-6 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 13 | Wed Dec 29 | at #10Michigan St | L68-81 | 6-7 | .462 | - | BTN | Breslin Center · East Lansing, MI |
| 14 | Fri Dec 31 | at #18Kentucky | L48-92 | 6-8 | .429 | - | SEC Network | Rupp Arena · Lexington, KY |
| 15 | Wed Jan 5 | vs Winthrop | PPD | 14-18 | .438 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 16 | Wed Jan 12 | at SC Upstate | L65-66 | 6-9 | .400 | - | | G.B. Hodge Center · Spartanburg, SC |
| 17 | Sat Jan 15 | vs NC A&T | W78-71 | 7-9 | .438 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 18 | Wed Jan 19 | at Charleston So | L66-70 | 7-10 | .412 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 19 | Sat Jan 22 | at Hampton | L64-68 (OT) | 7-11 | .389 | - | | Convocation Center (VA) · Hampton, VA |
| 20 | Mon Jan 24 | vsWinthrop | W65-56 | 8-11 | .421 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 21 | Wed Jan 26 | vs Radford | W63-58 | 9-11 | .450 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 22 | Sat Jan 29 | at Campbell | L72-77 | 9-12 | .429 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 23 | Wed Feb 2 | vs Gardner-Webb | L57-65 | 9-13 | .409 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 24 | Sat Feb 5 | vs UNC Asheville | W91-83 (OT) | 10-13 | .435 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 25 | Wed Feb 9 | at Presbyterian | W79-70 | 11-13 | .458 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 26 | Sat Feb 12 | vsCampbell | L42-60 | 11-14 | .440 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 27 | Tue Feb 15 | at Longwood | L66-70 | 11-15 | .423 | - | | Willett Hall · Farmville, VA |
| 28 | Thu Feb 17 | vsLongwood | L71-78 | 11-16 | .407 | - | ESPNU | Nido and Mariana Qubein Arena · High Point, NC |
| 29 | Sat Feb 19 | atRadford | L64-66 | 11-17 | .393 | - | | Donald N. Dedmon Center · Radford, VA |
| 30 | Wed Feb 23 | atNC A&T | W78-58 | 12-17 | .414 | - | | Corbett Sports Center · Greensboro, NC |
| 31 | Sat Feb 26 | vsHampton | W88-77 | 13-17 | .433 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 32 | Wed Mar 2 | vsHampton | W84-77 (OT) | 14-17 | .452 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 33 | Fri Mar 4 | atWinthrop | L51-68 | 14-18 | .438 | - | | Winthrop Coliseum · Rock Hill, SC |
