| 1 | Mon Nov 7 | vs TBD | W111-71 | 1-0 | 1.000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 2 | Sat Nov 12 | vs Wofford | W91-80 | 2-0 | 1.000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 3 | Tue Nov 15 | vsTBD | W100-83 | 3-0 | 1.000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 4 | Fri Nov 18 | at UNLV | L68-78 | 3-1 | .750 | - | | Thomas & Mack Center · Las Vegas, NV |
| 5 | Mon Nov 21 | vs C Michigan | W68-67 | 4-1 | .800 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 6 | Wed Nov 23 | vs Tennessee St | W77-72 | 5-1 | .833 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 7 | Wed Nov 30 | vs Elon | W84-70 | 6-1 | .857 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 8 | Sat Dec 3 | vs North Florida | W93-88 | 7-1 | .875 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 9 | Tue Dec 6 | at Furman | W85-82 | 8-1 | .889 | - | | Timmons Arena · Greenville, SC |
| 10 | Fri Dec 9 | vs Queens | L79-87 | 8-2 | .800 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 11 | Sun Dec 18 | at UNC Wilmington | L82-85 | 8-3 | .727 | - | | Trask Coliseum · Wilmington, NC |
| 12 | Wed Dec 21 | at E Carolina | L49-60 | 8-4 | .667 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 13 | Thu Dec 29 | at Longwood | L73-87 | 8-5 | .615 | - | | Willett Hall · Farmville, VA |
| 14 | Sat Dec 31 | vs Gardner-Webb | L73-80 | 8-6 | .571 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 15 | Wed Jan 4 | vs UNC Asheville | L72-76 | 8-7 | .533 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 16 | Sat Jan 7 | at SC Upstate | L57-76 | 8-8 | .500 | - | | G.B. Hodge Center · Spartanburg, SC |
| 17 | Wed Jan 11 | at Charleston So | L69-106 | 8-9 | .471 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 18 | Sat Jan 14 | vs Presbyterian | W64-56 | 9-9 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 19 | Wed Jan 18 | vs Winthrop | W71-66 | 10-9 | .526 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 20 | Sat Jan 21 | at Radford | L80-95 | 10-10 | .500 | - | | Donald N. Dedmon Center · Radford, VA |
| 21 | Wed Jan 25 | vs Campbell | L64-72 | 10-11 | .476 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 22 | Sat Jan 28 | atGardner-Webb | L58-86 | 10-12 | .455 | - | | Paul Porter Arena · Boiling Springs, NC |
| 23 | Thu Feb 2 | atUNC Asheville | L63-89 | 10-13 | .435 | - | ESPNU | Kimmel Arena · Asheville, NC |
| 24 | Sat Feb 4 | vsCharleston So | W81-73 | 11-13 | .458 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 25 | Wed Feb 8 | atCampbell | L66-82 | 11-14 | .440 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 26 | Sat Feb 11 | vsLongwood | L67-70 | 11-15 | .423 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 27 | Wed Feb 15 | atPresbyterian | W71-69 | 12-15 | .444 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 28 | Sat Feb 18 | vsSC Upstate | W81-66 | 13-15 | .464 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 29 | Wed Feb 22 | vsRadford | W69-64 | 14-15 | .483 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 30 | Sat Feb 25 | atWinthrop | L78-84 | 14-16 | .467 | - | | Winthrop Coliseum · Rock Hill, SC |
| 31 | Wed Mar 1 | vsCharleston So | L70-72 | 14-17 | .452 | - | | Nido and Mariana Qubein Arena · High Point, NC |
