| 1 | Mon Nov 3 | at Furman | 6:30 PM | 25-10 | .714 | - | | Timmons Arena · Greenville, SC |
| 2 | Sat Nov 8 | vsTBD | 5:00 PM | 0-0 | .000 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 3 | Tue Nov 11 | vsJacksonville | 7:00 PM | 19-14 | .576 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 4 | Fri Nov 14 | atUAB | 7:30 PM | 24-13 | .649 | - | ESPN+ | Bartow Arena · Birmingham, AL |
| 5 | Mon Nov 17 | vsCanisius | 7:00 PM | 3-28 | .097 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 6 | Thu Nov 20 | vsUIC | 2:30 PM | 17-14 | .548 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 7 | Sat Nov 29 | vsW Carolina | 2:00 PM | 8-22 | .267 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 8 | Wed Dec 3 | vsS Illinois | 7:00 PM | 14-19 | .424 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 9 | Fri Dec 5 | vsNJIT | 7:00 PM | 6-25 | .194 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 10 | Sun Dec 14 | vsAppalachian St | TBD | 17-14 | .548 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 11 | Tue Dec 16 | vsTBD | 7:00 PM | 0-0 | .000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 12 | Fri Dec 19 | vsLa Salle | 7:00 PM | 14-19 | .424 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 13 | Mon Dec 22 | vsBryant | 7:00 PM | 23-12 | .657 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 14 | Sun Dec 28 | vsTBD | 2:00 PM | 0-0 | .000 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 15 | Wed Dec 31 | atUNC Asheville | TBD | 21-11 | .656 | - | | Kimmel Arena · Asheville, NC |
| 16 | Sat Jan 3 | vsLongwood | 7:00 PM | 18-14 | .563 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 17 | Wed Jan 7 | vsGardner-Webb | 7:00 PM | 11-20 | .355 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 18 | Sat Jan 10 | atCharleston So | 2:00 PM | 10-22 | .313 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 19 | Wed Jan 14 | atWinthrop | TBD | 23-11 | .676 | - | | Winthrop Coliseum · Rock Hill, SC |
| 20 | Sat Jan 17 | vsSC Upstate | 7:00 PM | 6-26 | .188 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 21 | Sat Jan 24 | atRadford | TBD | 20-13 | .606 | - | | Donald N. Dedmon Center · Radford, VA |
| 22 | Thu Jan 29 | vsPresbyterian | 7:00 PM | 14-19 | .424 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 23 | Sat Jan 31 | atLongwood | TBD | 18-14 | .563 | - | | Willett Hall · Farmville, VA |
| 24 | Wed Feb 4 | vsCharleston So | 7:00 PM | 10-22 | .313 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 25 | Sat Feb 7 | vsRadford | 7:00 PM | 20-13 | .606 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 26 | Thu Feb 12 | atSC Upstate | 7:00 PM | 6-26 | .188 | - | | G.B. Hodge Center · Spartanburg, SC |
| 27 | Sat Feb 14 | atGardner-Webb | 2:00 PM | 11-20 | .355 | - | | Paul Porter Arena · Boiling Springs, NC |
| 28 | Thu Feb 19 | vsUNC Asheville | 7:00 PM | 21-11 | .656 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 29 | Sat Feb 21 | vsWinthrop | 4:00 PM | 23-11 | .676 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 30 | Thu Feb 26 | atPresbyterian | TBD | 14-19 | .424 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
