| 1 | Wed Nov 10 | vs FAMU | W67-57 | 1-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 2 | Wed Nov 17 | vs Omaha | W79-64 | 2-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 3 | Mon Nov 22 | vs Arkansas | L64-72 | 2-1 | .667 | - | ESPNEWS | Bramlage Coliseum · Manhattan, KS |
| 4 | Tue Nov 23 | vs Illinois | L64-72 | 2-2 | .500 | - | ESPNEWS | Bramlage Coliseum · Manhattan, KS |
| 5 | Sun Nov 28 | vs North Dakota | W84-42 | 3-2 | .600 | - | | Bramlage Coliseum · Manhattan, KS |
| 6 | Wed Dec 1 | vs Albany | W71-43 | 4-2 | .667 | - | | Bramlage Coliseum · Manhattan, KS |
| 7 | Sun Dec 5 | at Wichita St | W65-59 | 5-2 | .714 | - | ESPNU | Charles Koch Arena · Wichita, KS |
| 8 | Wed Dec 8 | vs Marquette | L63-64 | 5-3 | .625 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 9 | Sun Dec 12 | vs Green Bay | W82-64 | 6-3 | .667 | - | | Bramlage Coliseum · Manhattan, KS |
| 10 | Sun Dec 19 | at Nebraska | W67-58 | 7-3 | .700 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 11 | Tue Dec 21 | vs McNeese | W74-59 | 8-3 | .727 | - | | Bramlage Coliseum · Manhattan, KS |
| 13 | Sat Jan 1 | at Oklahoma | L69-71 | 8-4 | .667 | - | ESPNU | Lloyd Noble Center · Norman, OK |
| 14 | Tue Jan 4 | vs #14Texas | L57-70 | 8-5 | .615 | - | | Bramlage Coliseum · Manhattan, KS |
| 15 | Sat Jan 8 | at West Virginia | L68-71 | 8-6 | .571 | - | | WVU Coliseum · Morgantown, WV |
| 16 | Wed Jan 12 | vs TCU | L57-60 | 8-7 | .533 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 17 | Sat Jan 15 | vs #19Texas Tech | W62-51 | 9-7 | .563 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 18 | Tue Jan 18 | at#23Texas | W66-65 | 10-7 | .588 | - | LHN | Moody Center · Austin, TX |
| 19 | Sat Jan 22 | vs #7Kansas | L75-78 | 10-8 | .556 | - | | Bramlage Coliseum · Manhattan, KS |
| 20 | Tue Jan 25 | at #4Baylor | L49-74 | 10-9 | .526 | - | | Ferrell Center · Waco, TX |
| 21 | Sat Jan 29 | at Ole Miss | L56-67 | 10-10 | .500 | - | ESPNU | SJB Pavilion · Oxford, MS |
| 22 | Wed Feb 2 | vs Oklahoma St | W71-68 | 11-10 | .524 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 23 | Sat Feb 5 | atTCU | W75-63 | 12-10 | .545 | - | ESPNU | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 24 | Wed Feb 9 | vs#10Baylor | L60-75 | 12-11 | .522 | - | | Bramlage Coliseum · Manhattan, KS |
| 25 | Sat Feb 12 | at Iowa State | W75-69 (OT) | 13-11 | .542 | - | ESPNU | James H. Hilton Coliseum · Ames, IA |
| 26 | Mon Feb 14 | vsWest Virginia | W78-73 | 14-11 | .560 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 27 | Sat Feb 19 | atOklahoma St | L79-82 (OT) | 14-12 | .538 | - | ESPNU | Gallagher-Iba Arena · Stillwater, OK |
| 28 | Tue Feb 22 | at#5Kansas | L83-102 | 14-13 | .519 | - | ESPN | Allen Fieldhouse · Lawrence, KS |
| 29 | Sat Feb 26 | vsIowa State | L73-74 | 14-14 | .500 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 30 | Mon Feb 28 | at#12Texas Tech | L68-73 | 14-15 | .483 | - | ESPN2 | United Supermarkets Arena · Lubbock, TX |
| 31 | Sat Mar 5 | vsOklahoma | L71-78 | 14-16 | .467 | - | | Bramlage Coliseum · Manhattan, KS |
| 32 | Wed Mar 9 | vsWest Virginia | L67-73 | 14-17 | .452 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
North Florida