| 1 | Tue Nov 4 | vs UNC Greensboro | 8:00 PM | 20-12 | .625 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 2 | Sat Nov 8 | vsBellarmine | 8:00 PM | 5-26 | .161 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 3 | Thu Nov 13 | vsCalifornia | 9:00 PM | 14-19 | .424 | - | CBS | Bramlage Coliseum · Manhattan, KS |
| 4 | Mon Nov 17 | vsTulsa | 8:00 PM | 13-20 | .394 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 5 | Thu Nov 20 | vsMississippi St | 9:30 PM | 21-13 | .618 | - | Peacock | Bramlage Coliseum · Manhattan, KS |
| 6 | Tue Nov 25 | atIndiana | 8:00 PM | 19-13 | .594 | - | FS1 | Simon Skjodt Assembly Hall · Bloomington, IN |
| 7 | Mon Dec 1 | vsBowling Green | 8:00 PM | 14-18 | .438 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 8 | Sat Dec 6 | vsSeton Hall | 4:00 PM | 7-25 | .219 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 9 | Mon Dec 8 | vsMiss Valley St | 8:00 PM | 3-28 | .097 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 10 | Sat Dec 13 | at#23Creighton | 3:00 PM | 25-11 | .694 | - | FOX | CHI Health Center Omaha · Omaha, NE |
| 11 | Sat Dec 20 | vsSouth Dakota | 12:00 PM | 19-14 | .576 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 12 | Sun Dec 28 | vsUL Monroe | 2:00 PM | 7-25 | .219 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 13 | Sat Jan 3 | vs#8BYU | 1:30 PM | 26-10 | .722 | - | CBS | Bramlage Coliseum · Manhattan, KS |
| 14 | Wed Jan 7 | at#13Arizona | 9:00 PM | 24-13 | .649 | - | FS1 | McKale Center · Tucson, AZ |
| 15 | Sat Jan 10 | atArizona St | 3:00 PM | 13-20 | .394 | - | Peacock | Desert Financial Arena · Tempe, AZ |
| 16 | Wed Jan 14 | vsUCF | 8:00 PM | 20-17 | .541 | - | Peacock | Bramlage Coliseum · Manhattan, KS |
| 17 | Sat Jan 17 | atOklahoma St | 10:00 PM | 17-18 | .486 | - | CBS | Gallagher-Iba Arena · Stillwater, OK |
| 18 | Tue Jan 20 | vsUtah | 9:00 PM | 16-17 | .485 | - | CBS | Bramlage Coliseum · Manhattan, KS |
| 19 | Sat Jan 24 | vs#19Kansas | 8:00 PM | 21-13 | .618 | - | FOX | Bramlage Coliseum · Manhattan, KS |
| 20 | Tue Jan 27 | atWest Virginia | 8:30 PM | 19-13 | .594 | - | FS1 | WVU Coliseum · Morgantown, WV |
| 21 | Sun Feb 1 | vs#16Iowa State | 2:00 PM | 25-10 | .714 | - | FOX | Bramlage Coliseum · Manhattan, KS |
| 22 | Sat Feb 7 | atTCU | 9:30 PM | 16-16 | .500 | - | ESPN2 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 23 | Wed Feb 11 | vsCincinnati | TBD | 19-16 | .543 | - | CBS | Bramlage Coliseum · Manhattan, KS |
| 24 | Sat Feb 14 | at#2Houston | 9:00 PM | 35-5 | .875 | - | Peacock | Fertitta Center · Houston, TX |
| 25 | Tue Feb 17 | vsBaylor | 9:00 PM | 20-15 | .571 | - | | Bramlage Coliseum · Manhattan, KS |
| 26 | Sat Feb 21 | at#10Texas Tech | 2:30 PM | 28-9 | .757 | - | FOX | United Supermarkets Arena · Lubbock, TX |
| 27 | Wed Feb 25 | atColorado | 9:00 PM | 14-21 | .400 | - | FS1 | CU Events Center · Boulder, CO |
| 28 | Sat Feb 28 | vsTCU | 6:30 PM | 16-16 | .500 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 29 | Tue Mar 3 | vsWest Virginia | 8:00 PM | 19-13 | .594 | - | ESPN+ | Bramlage Coliseum · Manhattan, KS |
| 30 | Sat Mar 7 | at#19Kansas | 2:00 PM | 21-13 | .618 | - | CBS | Allen Fieldhouse · Lawrence, KS |
