| 1 | Mon Nov 7 | vs UT Rio Grande | W93-59 | 1-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 2 | Fri Nov 11 | at California | W63-54 | 2-0 | 1.000 | - | PACN | Haas Pavilion · Berkeley, CA |
| 3 | Thu Nov 17 | vs Kansas City | W69-53 | 3-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 4 | Mon Nov 21 | vs Rhode Island | W77-57 | 4-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 5 | Tue Nov 22 | vs Nevada | W96-87 (OT) | 5-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 6 | Wed Nov 23 | vs LSU | W61-59 | 6-0 | 1.000 | - | | Bramlage Coliseum · Manhattan, KS |
| 7 | Wed Nov 30 | at Butler | L64-76 | 6-1 | .857 | - | FS1 | Hinkle Fieldhouse · Indianapolis, IN |
| 8 | Sat Dec 3 | vs Wichita St | W55-50 | 7-1 | .875 | - | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 9 | Tue Dec 6 | vs Abilene Chrstn | W81-64 | 8-1 | .889 | - | | Bramlage Coliseum · Manhattan, KS |
| 10 | Sun Dec 11 | vs Incarnate Word | W98-50 | 9-1 | .900 | - | | Bramlage Coliseum · Manhattan, KS |
| 11 | Sat Dec 17 | vs Nebraska | W71-56 | 10-1 | .909 | - | | Bramlage Coliseum · Manhattan, KS |
| 12 | Wed Dec 21 | vs Radford | W73-65 | 11-1 | .917 | - | | Bramlage Coliseum · Manhattan, KS |
| 13 | Sat Dec 31 | vs #24West Virginia | W82-76 (OT) | 12-1 | .923 | - | | Bramlage Coliseum · Manhattan, KS |
| 14 | Tue Jan 3 | at #6Texas | W116-103 | 13-1 | .929 | - | LHN | Moody Center · Austin, TX |
| 15 | Sat Jan 7 | at #19Baylor | W97-95 (OT) | 14-1 | .933 | - | | Ferrell Center · Waco, TX |
| 16 | Tue Jan 10 | vs Oklahoma St | W65-57 | 15-1 | .938 | #11 | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 17 | Sat Jan 14 | at #17TCU | L68-82 | 15-2 | .882 | #11 | ESPN2 | Ed and Rae Schollmaier Arena · Fort Worth, TX |
| 18 | Tue Jan 17 | vs #2Kansas | W83-82 (OT) | 16-2 | .889 | #13 | ESPN | Bramlage Coliseum · Manhattan, KS |
| 19 | Sat Jan 21 | vs Texas Tech | W68-58 | 17-2 | .895 | #13 | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 20 | Tue Jan 24 | at #12Iowa State | L76-80 | 17-3 | .850 | #5 | ESPNU | James H. Hilton Coliseum · Ames, IA |
| 21 | Sat Jan 28 | vs Florida | W64-50 | 18-3 | .857 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 22 | Tue Jan 31 | at#8Kansas | L78-90 | 18-4 | .818 | #7 | | Allen Fieldhouse · Lawrence, KS |
| 23 | Sat Feb 4 | vs#10Texas | L66-69 | 18-5 | .783 | #7 | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 24 | Tue Feb 7 | vs#17TCU | W82-61 | 19-5 | .792 | #12 | ESPNU | Bramlage Coliseum · Manhattan, KS |
| 25 | Sat Feb 11 | atTexas Tech | L63-71 | 19-6 | .760 | #12 | | United Supermarkets Arena · Lubbock, TX |
| 26 | Tue Feb 14 | at Oklahoma | L65-79 | 19-7 | .731 | #12 | ESPNU | Lloyd Noble Center · Norman, OK |
| 27 | Sat Feb 18 | vs#19Iowa State | W61-55 | 20-7 | .741 | #12 | ESPN | Bramlage Coliseum · Manhattan, KS |
| 28 | Tue Feb 21 | vs#9Baylor | W75-65 | 21-7 | .750 | #14 | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 29 | Sat Feb 25 | atOklahoma St | W73-68 | 22-7 | .759 | #14 | ESPNU | Gallagher-Iba Arena · Stillwater, OK |
| 30 | Wed Mar 1 | vsOklahoma | W85-69 | 23-7 | .767 | #11 | | Bramlage Coliseum · Manhattan, KS |
| 31 | Sat Mar 4 | atWest Virginia | L81-89 | 23-8 | .742 | #11 | | WVU Coliseum · Morgantown, WV |
| 32 | Thu Mar 9 | vsTCU | L67-80 | 23-9 | .719 | - | ESPN2 | Bramlage Coliseum · Manhattan, KS |
| 33 | Fri Mar 17 | vs #14Montana St | W77-65 | 24-9 | .727 | #3 | CBS | Bramlage Coliseum · Manhattan, KS |
| 34 | Sun Mar 19 | vs #6Kentucky | W75-69 | 25-9 | .735 | #3 | CBS | Bramlage Coliseum · Manhattan, KS |
| 35 | Thu Mar 23 | vs #7Michigan St | W98-93 (OT) | 26-9 | .743 | #3 | TBS | Bramlage Coliseum · Manhattan, KS |
| 36 | Sat Mar 25 | vs #9FAU | L76-79 | 26-10 | .722 | #3 | TBS | Bramlage Coliseum · Manhattan, KS |
