| 1 | Tue Nov 5 | vs Fresno St | W71-57 | 1-0 | 1.000 | #15 | PACN | Matthew Knight Arena · Eugene, OR |
| 2 | Sat Nov 9 | vs Boise St | W106-75 | 2-0 | 1.000 | #15 | PACN | Matthew Knight Arena · Eugene, OR |
| 3 | Tue Nov 12 | at Memphis | W82-74 | 3-0 | 1.000 | - | ESPN | FedExForum · Memphis, TN |
| 4 | Sun Nov 17 | vs UT Arlington | W67-47 | 4-0 | 1.000 | #14 | PACN | Matthew Knight Arena · Eugene, OR |
| 5 | Fri Nov 22 | vs Houston | W78-66 | 5-0 | 1.000 | #11 | PACN | Matthew Knight Arena · Eugene, OR |
| 6 | Wed Nov 27 | at Seton Hall | W71-69 | 6-0 | 1.000 | - | ESPN2 | Prudential Center · Newark, NJ |
| 7 | Thu Nov 28 | at Gonzaga | L72-73 (OT) | 6-1 | .857 | - | ESPN | McCarthey Athletic Center · Spokane, WA |
| 8 | Fri Nov 29 | at UNC | L74-78 | 6-2 | .750 | - | ESPN | Dean E. Smith Center · Chapel Hill, NC |
| 9 | Sat Dec 7 | vs Hawai'i | W89-64 | 7-2 | .778 | #13 | PACN | Matthew Knight Arena · Eugene, OR |
| 10 | Sat Dec 14 | at #5Michigan | W71-70 (OT) | 8-2 | .800 | #10 | CBS | Crisler Center · Ann Arbor, MI |
| 11 | Wed Dec 18 | vs Montana | W81-48 | 9-2 | .818 | #8 | PACN | Matthew Knight Arena · Eugene, OR |
| 12 | Sat Dec 21 | vs Texas So | W84-78 | 10-2 | .833 | #8 | PACN | Matthew Knight Arena · Eugene, OR |
| 13 | Sun Dec 29 | vs Alabama St | W98-59 | 11-2 | .846 | #6 | PACN | Matthew Knight Arena · Eugene, OR |
| 14 | Thu Jan 2 | at Colorado | L65-74 | 11-3 | .786 | #4 | ESPN2 | CU Events Center · Boulder, CO |
| 15 | Sat Jan 4 | at Utah | W69-64 | 12-3 | .800 | #4 | PACN | Jon M. Huntsman Center · Salt Lake City, UT |
| 16 | Thu Jan 9 | vs #24Arizona | W74-73 (OT) | 13-3 | .813 | #9 | ESPN | Matthew Knight Arena · Eugene, OR |
| 17 | Sat Jan 11 | vs Arizona St | W78-69 | 14-3 | .824 | #9 | PACN | Matthew Knight Arena · Eugene, OR |
| 18 | Thu Jan 16 | at Washington St | L61-72 | 14-4 | .778 | #8 | FS1 | Friel Court at Beasley Coliseum · Pullman, WA |
| 19 | Sat Jan 18 | at Washington | W64-61 (OT) | 15-4 | .789 | #8 | CBS | Alaska Airlines Arena · Seattle, WA |
| 20 | Thu Jan 23 | vs USC | W79-70 (2OT) | 16-4 | .800 | #12 | ESPNU | Matthew Knight Arena · Eugene, OR |
| 21 | Sun Jan 26 | vs UCLA | W96-75 | 17-4 | .810 | #12 | | Matthew Knight Arena · Eugene, OR |
| 22 | Thu Jan 30 | at California | W77-72 | 18-4 | .818 | #11 | PACN | Haas Pavilion · Berkeley, CA |
| 23 | Sat Feb 1 | at Stanford | L60-70 | 18-5 | .783 | #11 | PACN | Maples Pavilion · Stanford, CA |
| 24 | Sat Feb 8 | at Oregon St | L53-63 | 18-6 | .750 | #14 | PACN | Gill Coliseum · Corvallis, OR |
| 25 | Thu Feb 13 | vs#16Colorado | W68-60 | 19-6 | .760 | #17 | ESPN | Matthew Knight Arena · Eugene, OR |
| 26 | Sun Feb 16 | vsUtah | W80-62 | 20-6 | .769 | #17 | FS1 | Matthew Knight Arena · Eugene, OR |
| 27 | Thu Feb 20 | atArizona St | L72-77 | 20-7 | .741 | #14 | ESPN | Desert Financial Arena · Tempe, AZ |
| 28 | Sat Feb 22 | at#24Arizona | W73-72 (OT) | 21-7 | .750 | #14 | ESPN | McKale Center · Tucson, AZ |
| 29 | Thu Feb 27 | vsOregon St | W69-54 | 22-7 | .759 | #14 | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 30 | Thu Mar 5 | vsCalifornia | W90-56 | 23-7 | .767 | #13 | ESPN2 | Matthew Knight Arena · Eugene, OR |
| 31 | Sat Mar 7 | vsStanford | W80-67 | 24-7 | .774 | #13 | FS1 | Matthew Knight Arena · Eugene, OR |
