| 1 | Wed Nov 25 | vs TBD | W88-49 | 1-0 | 1.000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 2 | Sat Nov 28 | vsTBD | W111-37 | 2-0 | 1.000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 5 | Mon Dec 7 | at #19Richmond | L72-77 | 2-1 | .667 | - | | Robins Center · Richmond, VA |
| 7 | Sat Dec 12 | at South Florida | L56-58 | 2-2 | .500 | - | ESPNEWS | Yuengling Center · Tampa, FL |
| 8 | Tue Dec 15 | vs Coast Car | W88-77 | 3-2 | .600 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 9 | Mon Dec 21 | at Texas A&M | L52-70 | 3-3 | .500 | - | SEC Network | Reed Arena · College Station, TX |
| 10 | Tue Dec 29 | at Mercer | W78-65 | 4-3 | .571 | - | ESPNU | Hawkins Arena · Macon, GA |
| 11 | Sat Jan 2 | vs Samford | W94-84 | 5-3 | .625 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 12 | Wed Jan 6 | vs UNC Greensboro | L75-84 | 5-4 | .556 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 13 | Sat Jan 9 | atUNC Greensboro | W48-45 | 6-4 | .600 | - | | Greensboro Coliseum · Greensboro, NC |
| 14 | Wed Jan 13 | at VMI | W80-78 | 7-4 | .636 | - | | Cameron Hall · Lexington, VA |
| 15 | Sat Jan 16 | at Chattanooga | W77-59 | 8-4 | .667 | - | | McKenzie Arena · Chattanooga, TN |
| 16 | Sat Jan 23 | vs W Carolina | W91-78 | 9-4 | .692 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 17 | Wed Jan 27 | at The Citadel | L69-77 | 9-5 | .643 | - | | McAlister Field House · Charleston, SC |
| 18 | Sat Jan 30 | vsMercer | W72-69 | 10-5 | .667 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 19 | Mon Feb 1 | vs ETSU | W67-62 | 11-5 | .688 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 20 | Wed Feb 3 | vsVMI | L80-84 (OT) | 11-6 | .647 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 21 | Sat Feb 6 | at Furman | W75-67 | 12-6 | .667 | - | | Timmons Arena · Greenville, SC |
| 22 | Wed Feb 10 | vsChattanooga | L66-78 | 12-7 | .632 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 23 | Sat Feb 13 | atETSU | L49-71 | 12-8 | .600 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 24 | Wed Feb 17 | vsThe Citadel | W81-67 | 13-8 | .619 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 25 | Sat Feb 20 | atW Carolina | W80-56 | 14-8 | .636 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 27 | Sat Feb 27 | vsFurman | W74-73 | 15-8 | .652 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 28 | Sat Mar 6 | vsMercer | L61-62 | 15-9 | .625 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
NC Central
Presbyterian
South Carolina