| 1 | Mon Nov 6 | vs TBD | W85-68 | 1-0 | 1.000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 2 | Sat Nov 11 | vs High Point | W99-98 | 2-0 | 1.000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 3 | Tue Nov 14 | at #7Tennessee | L61-82 | 2-1 | .667 | - | | Thompson-Boling Arena · Knoxville, TN |
| 4 | Sun Nov 19 | at Virginia Tech | L76-98 | 2-2 | .500 | - | | Cassell Coliseum · Blacksburg, VA |
| 5 | Fri Nov 24 | vs Canisius | L67-76 | 2-3 | .400 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 6 | Sat Nov 25 | at UNC Asheville | L82-85 (OT) | 2-4 | .333 | - | | Kimmel Arena · Asheville, NC |
| 7 | Sun Nov 26 | vs Lipscomb | L78-85 | 2-5 | .286 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 8 | Sat Dec 2 | at MTSU | W74-64 (OT) | 3-5 | .375 | - | | Murphy Center · Murfreesboro, TN |
| 9 | Wed Dec 6 | at Gardner-Webb | W81-66 | 4-5 | .444 | - | | Paul Porter Arena · Boiling Springs, NC |
| 10 | Sat Dec 9 | at Coast Car | W88-80 | 5-5 | .500 | - | | The HTC Center · Conway, SC |
| 11 | Sun Dec 17 | vsTBD | W105-54 | 6-5 | .545 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 12 | Wed Dec 20 | at Oklahoma St | L70-76 | 6-6 | .500 | - | | Gallagher-Iba Arena · Stillwater, OK |
| 13 | Fri Dec 29 | vsTBD | W75-55 | 7-6 | .538 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 14 | Wed Jan 3 | vs VMI | W87-85 (OT) | 8-6 | .571 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 15 | Sat Jan 6 | at W Carolina | L66-70 | 8-7 | .533 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 16 | Wed Jan 10 | vs Mercer | W74-73 | 9-7 | .563 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 17 | Sat Jan 13 | at The Citadel | W72-71 | 10-7 | .588 | - | | McAlister Field House · Charleston, SC |
| 18 | Wed Jan 17 | vs ETSU | W75-73 | 11-7 | .611 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 19 | Sat Jan 20 | at UNC Greensboro | L59-82 | 11-8 | .579 | - | | Greensboro Coliseum · Greensboro, NC |
| 20 | Wed Jan 24 | vs Chattanooga | L65-79 | 11-9 | .550 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 21 | Sat Jan 27 | vs Furman | W77-67 | 12-9 | .571 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 22 | Wed Jan 31 | at Samford | L79-81 | 12-10 | .545 | - | | Pete Hanna Center · Homewood, AL |
| 23 | Sat Feb 3 | vsW Carolina | W88-86 (OT) | 13-10 | .565 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 24 | Wed Feb 7 | atETSU | L50-57 | 13-11 | .542 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 25 | Sat Feb 10 | vsThe Citadel | W77-64 | 14-11 | .560 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 26 | Wed Feb 14 | atMercer | W73-60 | 15-11 | .577 | - | | Hawkins Arena · Macon, GA |
| 27 | Sat Feb 17 | vsUNC Greensboro | L47-58 | 15-12 | .556 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 28 | Wed Feb 21 | atChattanooga | L65-81 | 15-13 | .536 | - | | McKenzie Arena · Chattanooga, TN |
| 29 | Sat Feb 24 | atFurman | L67-82 | 15-14 | .517 | - | | Timmons Arena · Greenville, SC |
| 30 | Wed Feb 28 | vsSamford | W91-69 | 16-14 | .533 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 31 | Sat Mar 2 | atVMI | W74-62 | 17-14 | .548 | - | | Cameron Hall · Lexington, VA |
| 32 | Sat Mar 9 | atChattanooga | L57-75 | 17-15 | .531 | - | | McKenzie Arena · Chattanooga, TN |
