| 1 | Mon Nov 7 | vs TBD | W120-48 | 1-0 | 1.000 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 2 | Sat Nov 12 | at High Point | L80-91 | 1-1 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 3 | Mon Nov 14 | at Drake | L72-80 | 1-2 | .333 | - | | The Knapp Center · Des Moines, IA |
| 4 | Fri Nov 18 | vs Gardner-Webb | W60-58 | 2-2 | .500 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 5 | Sun Nov 20 | vs NC A&T | W78-64 | 3-2 | .600 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 6 | Wed Nov 23 | vsTBD | W70-59 | 4-2 | .667 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 7 | Sun Nov 27 | at LSU | L75-78 | 4-3 | .571 | - | | Pete Maravich Assembly Center · Baton Rouge, LA |
| 8 | Thu Dec 1 | vs Presbyterian | W76-63 | 5-3 | .625 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 9 | Sat Dec 3 | at Vanderbilt | L62-65 | 5-4 | .556 | - | | Memorial Gymnasium (TN) · Nashville, TN |
| 10 | Tue Dec 6 | vs Coast Car | W71-61 | 6-4 | .600 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 11 | Sat Dec 10 | at Georgia So | L57-79 | 6-5 | .545 | - | | W.S. Hanner Fieldhouse · Statesboro, GA |
| 12 | Sat Dec 17 | vsTBD | W107-65 | 7-5 | .583 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 13 | Tue Dec 20 | at Texas A&M | W67-62 | 8-5 | .615 | - | | Reed Arena · College Station, TX |
| 14 | Thu Dec 29 | vs ETSU | L71-73 | 8-6 | .571 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 15 | Sat Dec 31 | vs UNC Greensboro | L64-73 | 8-7 | .533 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 16 | Wed Jan 4 | at Mercer | W53-52 | 9-7 | .563 | - | | Hawkins Arena · Macon, GA |
| 17 | Sat Jan 7 | vs The Citadel | W77-57 | 10-7 | .588 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 18 | Wed Jan 11 | at Samford | L58-83 | 10-8 | .556 | - | | Pete Hanna Center · Homewood, AL |
| 19 | Sat Jan 14 | vs VMI | W86-67 | 11-8 | .579 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 20 | Wed Jan 18 | at W Carolina | L71-76 | 11-9 | .550 | - | | Ramsey Regional Activity Center · Cullowhee, NC |
| 21 | Sun Jan 22 | vs Furman | L82-96 | 11-10 | .524 | - | ESPNU | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 22 | Wed Jan 25 | at Chattanooga | W85-80 | 12-10 | .545 | - | | McKenzie Arena · Chattanooga, TN |
| 23 | Sat Jan 28 | vsSamford | W85-77 | 13-10 | .565 | - | CBS | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 24 | Wed Feb 1 | atETSU | L52-77 | 13-11 | .542 | - | | Freedom Hall Civic Center · Johnson City, TN |
| 25 | Sat Feb 4 | atFurman | L67-80 | 13-12 | .520 | - | | Timmons Arena · Greenville, SC |
| 26 | Wed Feb 8 | vsW Carolina | L91-95 (2OT) | 13-13 | .500 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 27 | Sun Feb 12 | atUNC Greensboro | L89-97 (OT) | 13-14 | .481 | - | | Greensboro Coliseum · Greensboro, NC |
| 28 | Wed Feb 15 | vsMercer | W70-67 | 14-14 | .500 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 29 | Sat Feb 18 | atThe Citadel | W72-68 | 15-14 | .517 | - | | McAlister Field House · Charleston, SC |
| 30 | Wed Feb 22 | atVMI | L83-87 (OT) | 15-15 | .500 | - | | Cameron Hall · Lexington, VA |
| 31 | Sat Feb 25 | vsChattanooga | W86-74 | 16-15 | .516 | - | | Jerry Richardson Indoor Stadium · Spartanburg, SC |
| 32 | Sat Mar 4 | atUNC Greensboro | W67-66 | 17-15 | .531 | - | | Greensboro Coliseum · Greensboro, NC |
| 33 | Sun Mar 5 | vsChattanooga | L62-74 | 17-16 | .515 | - | ESPNEWS | Jerry Richardson Indoor Stadium · Spartanburg, SC |
