| 1 | Wed Nov 25 | vs Ball State | W74-73 | 1-0 | 1.000 | - | | Truist Arena · Highland Heights, KY |
| 2 | Sat Nov 28 | atChattanooga | PPD | 14-11 | .560 | - | | McKenzie Arena · Chattanooga, TN |
| 3 | Thu Dec 3 | vsTennessee Tech | W74-65 | 2-0 | 1.000 | - | | Truist Arena · Highland Heights, KY |
| 4 | Sat Dec 5 | atChattanooga | L72-79 | 2-1 | .667 | - | | McKenzie Arena · Chattanooga, TN |
| 6 | Tue Dec 8 | atDayton | L60-66 | 2-2 | .500 | - | | UD Arena · Dayton, OH |
| 7 | Sun Dec 13 | atKent State | L73-92 | 2-3 | .400 | - | | M.A.C. Center · Kent, OH |
| 8 | Sat Dec 19 | vsYoungstown St | W79-64 | 3-3 | .500 | - | | Truist Arena · Highland Heights, KY |
| 9 | Sun Dec 20 | vsYoungstown St | L60-70 | 3-4 | .429 | - | ESPN2 | Truist Arena · Highland Heights, KY |
| 10 | Fri Jan 1 | vsPurdue FW | W75-68 | 4-4 | .500 | - | | Truist Arena · Highland Heights, KY |
| 11 | Sat Jan 2 | vsPurdue FW | W70-68 | 5-4 | .556 | - | | Truist Arena · Highland Heights, KY |
| 12 | Fri Jan 8 | atCleveland St | L44-58 | 5-5 | .500 | - | | Wolstein Center · Cleveland, OH |
| 13 | Sat Jan 9 | atCleveland St | L71-74 (OT) | 5-6 | .455 | - | | Wolstein Center · Cleveland, OH |
| 14 | Fri Jan 15 | vsIU Indy | L69-74 | 5-7 | .417 | - | | Truist Arena · Highland Heights, KY |
| 15 | Sat Jan 16 | vsIU Indy | L63-65 | 5-8 | .385 | - | | Truist Arena · Highland Heights, KY |
| 16 | Fri Jan 22 | atRobert Morris | W81-76 | 6-8 | .429 | - | | UPMC Events Center · Moon Township, PA |
| 17 | Sat Jan 23 | atRobert Morris | W79-74 (OT) | 7-8 | .467 | - | | UPMC Events Center · Moon Township, PA |
| 18 | Fri Jan 29 | vsUIC | W72-68 | 8-8 | .500 | - | | Truist Arena · Highland Heights, KY |
| 19 | Sat Jan 30 | vsUIC | W69-67 | 9-8 | .529 | - | | Truist Arena · Highland Heights, KY |
| 20 | Fri Feb 5 | atMilwaukee | W87-73 | 10-8 | .556 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 21 | Sat Feb 6 | atMilwaukee | W79-65 | 11-8 | .579 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 22 | Fri Feb 12 | atGreen Bay | L82-86 (OT) | 11-9 | .550 | - | | Resch Center · Ashwaubenon, WI |
| 23 | Sat Feb 13 | atGreen Bay | W71-66 | 12-9 | .571 | - | | Resch Center · Ashwaubenon, WI |
| 24 | Fri Feb 19 | vsWright St | W81-75 | 13-9 | .591 | - | | Truist Arena · Highland Heights, KY |
| 25 | Sat Feb 20 | vsWright St | L71-77 | 13-10 | .565 | - | | Truist Arena · Highland Heights, KY |
| 26 | Tue Mar 2 | vsDetroit Mercy | W70-69 | 14-10 | .583 | - | | Truist Arena · Highland Heights, KY |
| 27 | Mon Mar 8 | atOakland | L58-69 | 14-11 | .560 | - | ESPN2 | Indiana Farmers Coliseum · Indianapolis, IN |
