| 1 | Mon Nov 7 | vs Kent State | L57-79 | 0-1 | .000 | - | | Truist Arena · Highland Heights, KY |
| 2 | Sat Nov 12 | vs TBD | W89-49 | 1-1 | .500 | - | | Truist Arena · Highland Heights, KY |
| 3 | Wed Nov 16 | vs Cincinnati | W64-51 | 2-1 | .667 | - | | Truist Arena · Highland Heights, KY |
| 4 | Mon Nov 21 | vs FGCU | L61-82 | 2-2 | .500 | - | | Truist Arena · Highland Heights, KY |
| 5 | Tue Nov 22 | at UT Arlington | L56-60 | 2-3 | .400 | - | | College Park Center · Arlington, TX |
| 6 | Wed Nov 23 | at Toledo | L69-82 | 2-4 | .333 | - | | Savage Arena · Toledo, OH |
| 7 | Sun Nov 27 | vs Tennessee Tech | W85-77 (2OT) | 3-4 | .429 | - | | Truist Arena · Highland Heights, KY |
| 8 | Thu Dec 1 | vs Youngstown St | W77-73 (2OT) | 4-4 | .500 | - | | Truist Arena · Highland Heights, KY |
| 9 | Sat Dec 3 | vs Robert Morris | W60-56 | 5-4 | .556 | - | | Truist Arena · Highland Heights, KY |
| 10 | Wed Dec 7 | at Washington St | L47-68 | 5-5 | .500 | - | | Friel Court at Beasley Coliseum · Pullman, WA |
| 11 | Wed Dec 14 | vs E Kentucky | W64-61 | 6-5 | .545 | - | | Truist Arena · Highland Heights, KY |
| 12 | Sun Dec 18 | vsTBD | W81-41 | 7-5 | .583 | - | | Truist Arena · Highland Heights, KY |
| 13 | Wed Dec 21 | at FAU | L52-67 | 7-6 | .538 | - | | FAU Arena · Boca Raton, FL |
| 14 | Thu Dec 29 | vs Wright St | W78-64 | 8-6 | .571 | - | | Truist Arena · Highland Heights, KY |
| 15 | Sat Dec 31 | at IU Indy | W55-42 | 9-6 | .600 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 16 | Fri Jan 6 | vs Oakland | L63-64 | 9-7 | .563 | - | | Truist Arena · Highland Heights, KY |
| 17 | Sun Jan 8 | vs Detroit Mercy | W78-76 (OT) | 10-7 | .588 | - | | Truist Arena · Highland Heights, KY |
| 18 | Thu Jan 12 | at Milwaukee | L75-80 | 10-8 | .556 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 19 | Sat Jan 14 | at Green Bay | W74-53 | 11-8 | .579 | - | | Resch Center · Ashwaubenon, WI |
| 20 | Thu Jan 19 | vs Cleveland St | W57-56 | 12-8 | .600 | - | | Truist Arena · Highland Heights, KY |
| 21 | Sat Jan 21 | vs Purdue FW | W74-54 | 13-8 | .619 | - | | Truist Arena · Highland Heights, KY |
| 22 | Thu Jan 26 | vsGreen Bay | W68-50 | 14-8 | .636 | - | | Truist Arena · Highland Heights, KY |
| 23 | Sat Jan 28 | vsMilwaukee | L74-75 | 14-9 | .609 | - | | Truist Arena · Highland Heights, KY |
| 24 | Thu Feb 2 | atRobert Morris | W65-52 | 15-9 | .625 | - | | UPMC Events Center · Moon Township, PA |
| 25 | Sat Feb 4 | atYoungstown St | L56-74 | 15-10 | .600 | - | | Beeghly Center · Youngstown, OH |
| 26 | Fri Feb 10 | atWright St | L65-83 | 15-11 | .577 | - | ESPNU | Nutter Center · Dayton, OH |
| 27 | Sun Feb 12 | vsIU Indy | W86-47 | 16-11 | .593 | - | | Truist Arena · Highland Heights, KY |
| 28 | Fri Feb 17 | atPurdue FW | W63-50 | 17-11 | .607 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 29 | Sun Feb 19 | atCleveland St | L63-64 | 17-12 | .586 | - | | Wolstein Center · Cleveland, OH |
| 30 | Thu Feb 23 | atDetroit Mercy | W67-64 | 18-12 | .600 | - | | Calihan Hall · Detroit, MI |
| 31 | Sat Feb 25 | atOakland | W78-69 | 19-12 | .613 | - | | Athletics Center O'rena · Rochester, MI |
| 32 | Thu Mar 2 | vsOakland | W81-74 | 20-12 | .625 | - | | Truist Arena · Highland Heights, KY |
| 33 | Mon Mar 6 | atYoungstown St | W75-63 | 21-12 | .636 | - | ESPNU | Beeghly Center · Youngstown, OH |
| 34 | Tue Mar 7 | atCleveland St | W63-61 | 22-12 | .647 | - | ESPN | Wolstein Center · Cleveland, OH |
| 35 | Thu Mar 16 | at #1Houston | L52-63 | 22-13 | .629 | #16 | TNT | Fertitta Center · Houston, TX |
