| 1 | Mon Nov 3 | at Grand Canyon | 9:00 PM | 26-8 | .765 | - | | GCU Arena · Phoenix, AZ |
| 2 | Fri Nov 7 | atOhio State | TBD | 17-15 | .531 | - | BTN | Value City Arena · Columbus, OH |
| 3 | Sun Nov 9 | vsTBD | 2:00 PM | 0-0 | .000 | - | ESPN+ | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 4 | Wed Nov 12 | atW Michigan | TBD | 12-20 | .375 | - | ESPN+ | University Arena (MI) · Kalamazoo, MI |
| 5 | Sat Nov 15 | vsTBD | 2:00 PM | 0-0 | .000 | - | ESPN+ | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 6 | Tue Nov 18 | atUtah | 9:00 PM | 16-17 | .485 | - | | Jon M. Huntsman Center · Salt Lake City, UT |
| 7 | Fri Nov 21 | atSaint Louis | TBD | 19-15 | .559 | - | ESPN+ | Chaifetz Arena · St. Louis, MO |
| 8 | Tue Nov 25 | vsChicago St | 7:00 PM | 4-28 | .125 | - | ESPN+ | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 9 | Fri Nov 28 | vsHoly Cross | 2:00 PM | 13-19 | .406 | - | ESPN+ | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 10 | Wed Dec 3 | atOakland | 7:00 PM | 16-18 | .471 | - | | Athletics Center O'rena · Rochester, MI |
| 11 | Sat Dec 6 | vsN Kentucky | 2:00 PM | 17-16 | .515 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 12 | Wed Dec 10 | vsE Michigan | 8:00 PM | 16-16 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 13 | Sun Dec 14 | vsDetroit Mercy | 5:00 PM | 8-24 | .250 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 14 | Sun Dec 21 | atNotre Dame | TBD | 15-18 | .455 | - | | Purcell Pavilion · South Bend, IN |
| 15 | Mon Dec 29 | atMilwaukee | TBD | 21-11 | .656 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 16 | Thu Jan 1 | vsGreen Bay | 2:00 PM | 4-28 | .125 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 17 | Sun Jan 4 | vsCleveland St | 2:00 PM | 23-13 | .639 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 18 | Wed Jan 7 | atYoungstown St | 7:00 PM | 21-13 | .618 | - | | Beeghly Center · Youngstown, OH |
| 19 | Sun Jan 11 | atRobert Morris | 1:00 PM | 26-9 | .743 | - | | UPMC Events Center · Moon Township, PA |
| 20 | Sun Jan 18 | vsMilwaukee | 2:00 PM | 21-11 | .656 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 21 | Wed Jan 21 | atDetroit Mercy | 7:00 PM | 8-24 | .250 | - | | Calihan Hall · Detroit, MI |
| 22 | Sun Jan 25 | atIU Indy | 2:00 PM | 10-22 | .313 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 23 | Wed Jan 28 | vsOakland | 7:00 PM | 16-18 | .471 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 24 | Sat Jan 31 | vsRobert Morris | 1:00 PM | 26-9 | .743 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 25 | Wed Feb 4 | vsYoungstown St | 7:00 PM | 21-13 | .618 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 26 | Sat Feb 7 | atWright St | TBD | 15-18 | .455 | - | | Nutter Center · Dayton, OH |
| 27 | Thu Feb 12 | atGreen Bay | 7:00 PM | 4-28 | .125 | - | | Resch Center · Ashwaubenon, WI |
| 28 | Sun Feb 15 | vsIU Indy | 2:00 PM | 10-22 | .313 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 29 | Wed Feb 18 | atN Kentucky | 7:00 PM | 17-16 | .515 | - | | Truist Arena · Highland Heights, KY |
| 30 | Sun Feb 22 | atCleveland St | 2:00 PM | 23-13 | .639 | - | | Wolstein Center · Cleveland, OH |
| 31 | Wed Feb 25 | vsWright St | 7:00 PM | 15-18 | .455 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
