| 1 | Mon Nov 7 | at #22Michigan | L56-75 | 0-1 | .000 | - | BTN | Crisler Center · Ann Arbor, MI |
| 2 | Sat Nov 12 | vs SIUE | W81-76 | 1-1 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 3 | Mon Nov 14 | vs TBD | W111-31 | 2-1 | .667 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 4 | Fri Nov 18 | at Northwestern | L52-60 | 2-2 | .500 | - | | Welsh-Ryan Arena · Evanston, IL |
| 5 | Tue Nov 22 | at E Michigan | W74-67 | 3-2 | .600 | - | | Convocation Center (MI) · Ypsilanti, MI |
| 6 | Wed Nov 23 | at Southern Miss | L58-70 | 3-3 | .500 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 7 | Sun Nov 27 | vsTBD | W106-41 | 4-3 | .571 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 8 | Thu Dec 1 | vs Detroit Mercy | L66-75 | 4-4 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 9 | Sat Dec 3 | vs Oakland | W79-73 (OT) | 5-4 | .556 | - | ESPNU | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 10 | Wed Dec 7 | at SE Missouri St | W89-68 | 6-4 | .600 | - | | Show Me Center · Cape Girardeau, MO |
| 11 | Sat Dec 10 | at Missouri St | W65-61 | 7-4 | .636 | - | | Great Southern Bank Arena · Springfield, MO |
| 12 | Mon Dec 19 | vs E Texas A&M | W85-68 | 8-4 | .667 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 13 | Tue Dec 20 | vs So Indiana | W83-59 | 9-4 | .692 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 14 | Thu Dec 29 | at Robert Morris | L70-75 | 9-5 | .643 | - | | UPMC Events Center · Moon Township, PA |
| 15 | Sat Dec 31 | at Youngstown St | W76-71 | 10-5 | .667 | - | | Beeghly Center · Youngstown, OH |
| 16 | Thu Jan 5 | vs Green Bay | W79-69 | 11-5 | .688 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 17 | Sat Jan 7 | vs Milwaukee | L70-74 | 11-6 | .647 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 18 | Thu Jan 12 | at IU Indy | W70-55 | 12-6 | .667 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 19 | Mon Jan 16 | vs Cleveland St | L60-72 | 12-7 | .632 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 20 | Thu Jan 19 | at Wright St | W88-80 | 13-7 | .650 | - | | Nutter Center · Dayton, OH |
| 21 | Sat Jan 21 | at N Kentucky | L54-74 | 13-8 | .619 | - | | Truist Arena · Highland Heights, KY |
| 22 | Wed Jan 25 | vsIU Indy | W81-75 | 14-8 | .636 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 23 | Fri Jan 27 | atCleveland St | L74-79 | 14-9 | .609 | - | | Wolstein Center · Cleveland, OH |
| 24 | Thu Feb 2 | atOakland | W82-73 | 15-9 | .625 | - | | Athletics Center O'rena · Rochester, MI |
| 25 | Sat Feb 4 | atDetroit Mercy | L52-85 | 15-10 | .600 | - | | Calihan Hall · Detroit, MI |
| 26 | Fri Feb 10 | vsYoungstown St | L72-81 | 15-11 | .577 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 27 | Sun Feb 12 | vsRobert Morris | L64-71 | 15-12 | .556 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 28 | Fri Feb 17 | vsN Kentucky | L50-63 | 15-13 | .536 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 29 | Sun Feb 19 | vsWright St | W77-75 | 16-13 | .552 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 30 | Thu Feb 23 | atMilwaukee | L94-96 | 16-14 | .533 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 31 | Sat Feb 25 | atGreen Bay | W78-61 | 17-14 | .548 | - | | Resch Center · Ashwaubenon, WI |
| 32 | Tue Feb 28 | atDetroit Mercy | L68-81 | 17-15 | .531 | - | | Calihan Hall · Detroit, MI |
