| 1 | Tue Nov 9 | vs Pepperdine | W82-63 | 1-0 | 1.000 | - | | Tudor Fieldhouse · Houston, TX |
| 2 | Fri Nov 12 | at #15Houston | L46-79 | 1-1 | .500 | - | | Fertitta Center · Houston, TX |
| 3 | Tue Nov 16 | vs Southern | W81-63 | 2-1 | .667 | - | | Tudor Fieldhouse · Houston, TX |
| 4 | Fri Nov 19 | at New Orleans | W83-78 | 3-1 | .750 | - | | Lakefront Arena · New Orleans, LA |
| 5 | Mon Nov 22 | vs Evansville | W109-104 (3OT) | 4-1 | .800 | - | | Tudor Fieldhouse · Houston, TX |
| 6 | Tue Nov 23 | vs Oakland | L73-76 | 4-2 | .667 | - | | Tudor Fieldhouse · Houston, TX |
| 7 | Wed Nov 24 | vs Fordham | L74-84 | 4-3 | .571 | - | | Tudor Fieldhouse · Houston, TX |
| 8 | Tue Nov 30 | vs Texas St | L69-80 | 4-4 | .500 | - | | Tudor Fieldhouse · Houston, TX |
| 9 | Sat Dec 4 | vs TBD | W100-62 | 5-4 | .556 | - | | Tudor Fieldhouse · Houston, TX |
| 10 | Sat Dec 11 | at Hou Christian | W88-73 | 6-4 | .600 | - | | Sharp Gymnasium · Houston, TX |
| 11 | Thu Dec 16 | vs Incarnate Word | W85-55 | 7-4 | .636 | - | | Tudor Fieldhouse · Houston, TX |
| 13 | Sat Jan 1 | at North Texas | L43-75 | 7-5 | .583 | - | | The Super Pit · Denton, TX |
| 14 | Thu Jan 6 | vs MTSU | W65-61 | 8-5 | .615 | - | | Tudor Fieldhouse · Houston, TX |
| 15 | Sat Jan 8 | vs UAB | W85-80 | 9-5 | .643 | - | | Tudor Fieldhouse · Houston, TX |
| 16 | Thu Jan 13 | at Western KY | L66-80 | 9-6 | .600 | - | CBS | E. A. Diddle Arena · Bowling Green, KY |
| 17 | Sat Jan 15 | at Marshall | W87-77 | 10-6 | .625 | - | | Cam Henderson Center · Huntington, WV |
| 18 | Thu Jan 20 | vs Old Dominion | W77-69 | 11-6 | .647 | - | | Tudor Fieldhouse · Houston, TX |
| 19 | Sat Jan 22 | vs Charlotte | L64-67 | 11-7 | .611 | - | | Tudor Fieldhouse · Houston, TX |
| 20 | Thu Jan 27 | at Louisiana Tech | L63-80 | 11-8 | .579 | - | | Thomas Assembly Center · Ruston, LA |
| 21 | Sat Jan 29 | at Southern Miss | W76-62 | 12-8 | .600 | - | | Reed Green Coliseum · Hattiesburg, MS |
| 22 | Thu Feb 3 | vs UTSA | W91-78 | 13-8 | .619 | - | | Tudor Fieldhouse · Houston, TX |
| 23 | Sat Feb 5 | vs UTEP | L70-72 | 13-9 | .591 | - | | Tudor Fieldhouse · Houston, TX |
| 24 | Tue Feb 8 | vsTBD | W98-63 | 14-9 | .609 | - | | Tudor Fieldhouse · Houston, TX |
| 25 | Sat Feb 12 | vsNorth Texas | L44-67 | 14-10 | .583 | - | | Tudor Fieldhouse · Houston, TX |
| 26 | Thu Feb 17 | atUAB | L68-92 | 14-11 | .560 | - | | Bartow Arena · Birmingham, AL |
| 27 | Sat Feb 19 | at FIU | L78-80 | 14-12 | .538 | - | | Ocean Bank Convocation Center · Miami, FL |
| 28 | Thu Feb 24 | vsLouisiana Tech | L79-83 | 14-13 | .519 | - | | Tudor Fieldhouse · Houston, TX |
| 29 | Sat Feb 26 | vsSouthern Miss | W77-72 (OT) | 15-13 | .536 | - | | Tudor Fieldhouse · Houston, TX |
| 30 | Thu Mar 3 | atUTEP | L67-70 | 15-14 | .517 | - | CBS | Don Haskins Center · El Paso, TX |
| 31 | Sat Mar 5 | atUTSA | L71-82 | 15-15 | .500 | - | | UTSA Convocation Center · San Antonio, TX |
| 32 | Wed Mar 9 | atCharlotte | W73-61 | 16-15 | .516 | - | | Dale F. Halton Arena · Charlotte, NC |
| 33 | Thu Mar 10 | atNorth Texas | L50-68 | 16-16 | .500 | - | | The Super Pit · Denton, TX |
| 34 | Sat Mar 19 | vs Ohio | L64-65 | 16-17 | .485 | - | | Tudor Fieldhouse · Houston, TX |
