| 1 | Tue Nov 4 | vs TBD | 8:00 PM | 0-0 | .000 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 2 | Fri Nov 7 | atOregon | TBD | 25-10 | .714 | - | B1G+ | Matthew Knight Arena · Eugene, OR |
| 3 | Tue Nov 11 | vsSF Austin | 8:00 PM | 14-17 | .452 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 4 | Fri Nov 14 | vsE Texas A&M | 8:00 PM | 5-26 | .161 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 5 | Mon Nov 17 | at#18Tennessee | 8:30 PM | 30-8 | .789 | - | SEC Network | Thompson-Boling Arena · Knoxville, TN |
| 6 | Thu Nov 20 | vsTarleton | 8:00 PM | 12-20 | .375 | - | ESPN+ | Tudor Fieldhouse · Houston, TX |
| 7 | Mon Nov 24 | atKennesaw St | 4:30 PM | 19-14 | .576 | - | | KSU Convocation Center · Kennesaw, GA |
| 8 | Tue Nov 25 | atFGCU | 7:00 PM | 19-15 | .559 | - | | Alico Arena · Fort Myers, FL |
| 9 | Wed Nov 26 | vsOral Roberts | 4:30 PM | 7-23 | .233 | - | | Tudor Fieldhouse · Houston, TX |
| 10 | Wed Dec 3 | vsTexas St | TBD | 16-16 | .500 | - | | Tudor Fieldhouse · Houston, TX |
| 11 | Sat Dec 13 | vsArkansas St | TBD | 25-11 | .694 | - | | Tudor Fieldhouse · Houston, TX |
| 12 | Wed Dec 17 | vsTBD | TBD | 0-0 | .000 | - | | Tudor Fieldhouse · Houston, TX |
| 13 | Sat Dec 20 | atPepperdine | TBD | 13-22 | .371 | - | | Firestone Fieldhouse · Malibu, CA |
| 14 | Wed Dec 31 | atTulsa | TBD | 13-20 | .394 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 15 | Sat Jan 3 | vsMemphis | TBD | 29-6 | .829 | - | | Tudor Fieldhouse · Houston, TX |
| 16 | Wed Jan 7 | atWichita St | TBD | 19-15 | .559 | - | | Charles Koch Arena · Wichita, KS |
| 17 | Sun Jan 11 | vsCharlotte | TBD | 11-22 | .333 | - | | Tudor Fieldhouse · Houston, TX |
| 18 | Wed Jan 14 | atUTSA | TBD | 12-19 | .387 | - | | UTSA Convocation Center · San Antonio, TX |
| 19 | Wed Jan 21 | vsTemple | TBD | 17-15 | .531 | - | | Tudor Fieldhouse · Houston, TX |
| 20 | Sun Jan 25 | vsTulsa | TBD | 13-20 | .394 | - | | Tudor Fieldhouse · Houston, TX |
| 21 | Wed Jan 28 | atE Carolina | TBD | 19-14 | .576 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 22 | Sat Jan 31 | atCharlotte | TBD | 11-22 | .333 | - | | Dale F. Halton Arena · Charlotte, NC |
| 23 | Wed Feb 4 | vsNorth Texas | TBD | 27-9 | .750 | - | | Tudor Fieldhouse · Houston, TX |
| 24 | Sun Feb 8 | atUAB | TBD | 24-13 | .649 | - | | Bartow Arena · Birmingham, AL |
| 25 | Wed Feb 11 | vsFAU | TBD | 18-16 | .529 | - | | Tudor Fieldhouse · Houston, TX |
| 26 | Sat Feb 14 | vsE Carolina | TBD | 19-14 | .576 | - | | Tudor Fieldhouse · Houston, TX |
| 27 | Sun Feb 22 | atTulane | TBD | 19-15 | .559 | - | | Devlin Fieldhouse · New Orleans, LA |
| 28 | Wed Feb 25 | vsSouth Florida | TBD | 13-19 | .406 | - | | Tudor Fieldhouse · Houston, TX |
| 29 | Sun Mar 1 | atTemple | TBD | 17-15 | .531 | - | | Liacouras Center · Philadelphia, PA |
| 30 | Wed Mar 4 | atNorth Texas | TBD | 27-9 | .750 | - | | The Super Pit · Denton, TX |
| 31 | Sun Mar 8 | vsUTSA | TBD | 12-19 | .387 | - | | Tudor Fieldhouse · Houston, TX |
