| 1 | Tue Nov 9 | vs McNeese | W86-62 | 1-0 | 1.000 | - | | Moody Coliseum · Dallas, TX |
| 2 | Fri Nov 12 | at #13Oregon | L63-86 | 1-1 | .500 | - | PACN | Matthew Knight Arena · Eugene, OR |
| 3 | Mon Nov 15 | vs N'Western St | W95-48 | 2-1 | .667 | - | | Moody Coliseum · Dallas, TX |
| 4 | Thu Nov 18 | vs SE Louisiana | W78-61 | 3-1 | .750 | - | | Moody Coliseum · Dallas, TX |
| 5 | Sun Nov 21 | vs Missouri | L75-80 (OT) | 3-2 | .600 | - | CBS | Moody Coliseum · Dallas, TX |
| 6 | Mon Nov 22 | vs LMU | L70-76 | 3-3 | .500 | - | | Moody Coliseum · Dallas, TX |
| 7 | Wed Nov 24 | vs Sam Houston | W75-66 | 4-3 | .571 | - | | Moody Coliseum · Dallas, TX |
| 8 | Sun Nov 28 | vs UL Monroe | W74-67 | 5-3 | .625 | - | | Moody Coliseum · Dallas, TX |
| 9 | Wed Dec 1 | vs UNLV | W83-64 | 6-3 | .667 | - | | Moody Coliseum · Dallas, TX |
| 10 | Sat Dec 4 | vs Vanderbilt | W84-72 | 7-3 | .700 | - | | Moody Coliseum · Dallas, TX |
| 11 | Wed Dec 8 | vs Dayton | W77-69 | 8-3 | .727 | - | | Moody Coliseum · Dallas, TX |
| 12 | Sun Dec 19 | at New Mexico | W90-72 | 9-3 | .750 | - | | The Pit · Albuquerque, NM |
| 14 | Wed Dec 29 | at Tulsa | W74-69 | 10-3 | .769 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 15 | Sun Jan 2 | vs UCF | W72-60 | 11-3 | .786 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 16 | Thu Jan 6 | at Cincinnati | L60-77 | 11-4 | .733 | - | ESPN | Fifth Third Arena · Cincinnati, OH |
| 17 | Wed Jan 12 | vs South Florida | W77-65 | 12-4 | .750 | - | | Moody Coliseum · Dallas, TX |
| 18 | Sat Jan 15 | at Tulane | W75-66 | 13-4 | .765 | - | | Devlin Fieldhouse · New Orleans, LA |
| 19 | Thu Jan 20 | at Memphis | W70-62 | 14-4 | .778 | - | ESPN2 | FedExForum · Memphis, TN |
| 20 | Sun Jan 23 | vs Wichita St | PPD | 24-9 | .727 | - | | Moody Coliseum · Dallas, TX |
| 21 | Wed Jan 26 | atSouth Florida | W74-54 | 15-4 | .789 | - | | Yuengling Center · Tampa, FL |
| 22 | Sat Jan 29 | vs Temple | W69-61 | 16-4 | .800 | - | | Moody Coliseum · Dallas, TX |
| 24 | Sat Feb 5 | atWichita St | L57-72 | 16-5 | .762 | - | ESPN2 | Charles Koch Arena · Wichita, KS |
| 25 | Wed Feb 9 | vs #6Houston | W85-83 | 17-5 | .773 | - | ESPN2 | Moody Coliseum · Dallas, TX |
| 26 | Sat Feb 12 | at E Carolina | W80-66 | 18-5 | .783 | - | ESPNU | Williams Arena at Minges Coliseum · Greenville, NC |
| 27 | Wed Feb 16 | atTemple | L57-64 | 18-6 | .750 | - | ESPNU | Liacouras Center · Philadelphia, PA |
| 28 | Sun Feb 20 | vsMemphis | W73-57 | 19-6 | .760 | - | ESPN | Moody Coliseum · Dallas, TX |
| 29 | Wed Feb 23 | vsTulsa | W75-61 | 20-6 | .769 | - | | Moody Coliseum · Dallas, TX |
| 30 | Sun Feb 27 | at#14Houston | L61-75 | 20-7 | .741 | - | ESPN | Fertitta Center · Houston, TX |
| 31 | Thu Mar 3 | vsCincinnati | W76-71 | 21-7 | .750 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 32 | Sun Mar 6 | vsTulane | W74-68 | 22-7 | .759 | - | | Moody Coliseum · Dallas, TX |
| 33 | Fri Mar 11 | vsTulsa | W83-58 | 23-7 | .767 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 34 | Sat Mar 12 | vsMemphis | L63-70 | 23-8 | .742 | - | ESPN2 | Moody Coliseum · Dallas, TX |
| 35 | Wed Mar 16 | vs Nicholls | W68-58 | 24-8 | .750 | - | | Moody Coliseum · Dallas, TX |
| 36 | Sun Mar 20 | vs Washington St | L63-75 | 24-9 | .727 | - | | Moody Coliseum · Dallas, TX |
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