| 1 | Mon Nov 7 | vs E Texas A&M | W77-60 | -17 | 1-0 | 1.000 | - | | Moody Coliseum · Dallas, TX |
| 2 | Fri Nov 11 | at24Dayton | L62-74 | +11 | 1-1 | .500 | - | | UD Arena · Dayton, OH |
| 3 | Tue Nov 15 | vsNew Mexico | L63-84 | -3½ | 1-2 | .333 | - | | Moody Coliseum · Dallas, TX |
| 4 | Sat Nov 19 | vsEvansville | W55-47 | -12½ | 2-2 | .500 | - | | Moody Coliseum · Dallas, TX |
| 5 | Tue Nov 22 | vsLouisiana | L72-76 (OT) | -1½ | 2-3 | .400 | - | | Moody Coliseum · Dallas, TX |
| 6 | Sun Nov 27 | vsLamar | W75-50 | -18 | 3-3 | .500 | - | | Moody Coliseum · Dallas, TX |
| 7 | Wed Nov 30 | atTexas A&M | L64-83 | +11 | 3-4 | .429 | - | | Reed Arena · College Station, TX |
| 8 | Sat Dec 3 | vsJackson St | L68-69 | -13 | 3-5 | .375 | - | | Moody Coliseum · Dallas, TX |
| 9 | Wed Dec 7 | vsArizona St | L57-75 | +5 | 3-6 | .333 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 10 | Sat Dec 10 | vs24TCU | L75-83 | -12 | 3-7 | .300 | - | ESPN2 | Moody Coliseum · Dallas, TX |
| 11 | Thu Dec 22 | vsIona | W85-81 | +9½ | 4-7 | .364 | - | ESPNU | Stan Sheriff Center · Honolulu, HI |
| 12 | Fri Dec 23 | atUtah State | W77-74 | +12½ | 5-7 | .417 | - | ESPN2 | Stan Sheriff Center · Honolulu, HI |
| 13 | Sun Dec 25 | atHawai'i | L57-58 | +4½ | 5-8 | .385 | - | ESPN2 | Stan Sheriff Center · Honolulu, HI |
| 14 | Sun Jan 1 | vsTulsa | W92-67 | -8 | 6-8 | .429 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 15 | Thu Jan 5 | at2Houston | L53-87 | +20½ | 6-9 | .400 | - | ESPN2 | Fertitta Center · Houston, TX |
| 16 | Sun Jan 8 | atUCF | L53-85 | +9½ | 6-10 | .375 | - | ESPNU | Addition Financial Arena · Orlando, FL |
| 17 | Wed Jan 11 | vsTulane | L88-97 | +4½ | 6-11 | .353 | - | | Moody Coliseum · Dallas, TX |
| 18 | Sat Jan 14 | vsCincinnati | L52-54 | +5½ | 6-12 | .333 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 19 | Wed Jan 18 | atTulsa | W79-76 (OT) | -3½ | 7-12 | .368 | - | | Donald W. Reynolds Center · Tulsa, OK |
| 20 | Sun Jan 22 | vsWichita St | L69-71 | -1½ | 7-13 | .350 | - | | Moody Coliseum · Dallas, TX |
| 21 | Thu Jan 26 | atMemphis | L84-99 | +12½ | 7-14 | .333 | - | ESPN2 | FedExForum · Memphis, TN |
| 22 | Sun Jan 29 | vsSouth Florida | W82-80 | -3 | 8-14 | .364 | - | ESPNU | Moody Coliseum · Dallas, TX |
| 23 | Wed Feb 1 | atTulane | L52-74 | +8½ | 8-15 | .348 | - | ESPNU | Devlin Fieldhouse · New Orleans, LA |
| 24 | Sat Feb 4 | atE Carolina | L72-77 | -2 | 8-16 | .333 | - | | Williams Arena at Minges Coliseum · Greenville, NC |
| 25 | Wed Feb 8 | vsTemple | W72-71 | +2 | 9-16 | .360 | - | | Moody Coliseum · Dallas, TX |
| 26 | Sun Feb 12 | atWichita St | L89-91 (2OT) | +6½ | 9-17 | .346 | - | ESPN | Charles Koch Arena · Wichita, KS |
| 27 | Thu Feb 16 | vs2Houston | L65-80 | +15½ | 9-18 | .333 | - | ESPN2 | Moody Coliseum · Dallas, TX |
| 28 | Sun Feb 19 | vsE Carolina | W86-70 | -7 | 10-18 | .357 | - | | Moody Coliseum · Dallas, TX |
| 29 | Sat Feb 25 | atSouth Florida | L67-71 | +4 | 10-19 | .345 | - | | Yuengling Center · Tampa, FL |
| 30 | Thu Mar 2 | vsMemphis | L62-81 | +6 | 10-20 | .333 | - | ESPN2 | Moody Coliseum · Dallas, TX |
| 31 | Sun Mar 5 | atCincinnati | L74-97 | +12½ | 10-21 | .323 | - | | Fifth Third Arena · Cincinnati, OH |
| 32 | Thu Mar 9 | atUCF | L70-76 | +7½ | 10-22 | .313 | - | ESPNU | Addition Financial Arena · Orlando, FL |
