| 1 | Tue Nov 7 | at #20Baylor | L82-88 | 0-1 | .000 | - | ESPN | Ferrell Center · Waco, TX |
| 2 | Fri Nov 10 | vs SE Louisiana | W86-71 | 1-1 | .500 | - | | Neville Arena · Auburn, AL |
| 3 | Thu Nov 16 | at Notre Dame | W83-59 | 2-1 | .667 | - | ESPN2 | Purcell Pavilion · South Bend, IN |
| 4 | Fri Nov 17 | at St Bonaventure | W77-60 | 3-1 | .750 | - | ESPN2 | Reilly Center · Saint Bonaventure, NY |
| 5 | Tue Nov 21 | vs Alabama A&M | W84-54 | 4-1 | .800 | - | | Neville Arena · Auburn, AL |
| 6 | Wed Nov 29 | vs Virginia Tech | W74-57 | 5-1 | .833 | - | ESPN2 | Neville Arena · Auburn, AL |
| 7 | Sun Dec 3 | at Appalachian St | L64-69 | 5-2 | .714 | - | ESPN2 | Holmes Convocation Center · Boone, NC |
| 8 | Sat Dec 9 | at Indiana | W104-76 | 6-2 | .750 | - | ESPN2 | Simon Skjodt Assembly Hall · Bloomington, IN |
| 9 | Wed Dec 13 | vs UNC Asheville | W87-62 | 7-2 | .778 | - | | Neville Arena · Auburn, AL |
| 10 | Sun Dec 17 | vs USC | W91-75 | 8-2 | .800 | - | ESPN | Neville Arena · Auburn, AL |
| 11 | Fri Dec 22 | vs Alabama St | W82-62 | 9-2 | .818 | - | | Neville Arena · Auburn, AL |
| 12 | Sat Dec 30 | vs Chattanooga | W101-66 | 10-2 | .833 | - | SEC Network | Neville Arena · Auburn, AL |
| 13 | Tue Jan 2 | vs Penn | W88-68 | 11-2 | .846 | #25 | SEC Network | Neville Arena · Auburn, AL |
| 14 | Sat Jan 6 | at Arkansas | W83-51 | 12-2 | .857 | #25 | ESPN2 | Bud Walton Arena · Fayetteville, AR |
| 15 | Tue Jan 9 | vs Texas A&M | W66-55 | 13-2 | .867 | #16 | ESPN2 | Neville Arena · Auburn, AL |
| 16 | Sat Jan 13 | vs LSU | W93-78 | 14-2 | .875 | #16 | SEC Network | Neville Arena · Auburn, AL |
| 17 | Wed Jan 17 | at Vanderbilt | W80-65 | 15-2 | .882 | #13 | SEC Network | Memorial Gymnasium (TN) · Nashville, TN |
| 18 | Sat Jan 20 | vs #22Ole Miss | W82-59 | 16-2 | .889 | #13 | SEC Network | Neville Arena · Auburn, AL |
| 19 | Wed Jan 24 | at Alabama | L75-79 | 16-3 | .842 | #8 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 20 | Sat Jan 27 | at Mississippi St | L58-64 | 16-4 | .800 | #8 | SEC Network | Humphrey Coliseum · Starkville, MS |
| 21 | Wed Jan 31 | vsVanderbilt | W81-54 | 17-4 | .810 | #16 | ESPN2 | Neville Arena · Auburn, AL |
| 22 | Sat Feb 3 | atOle Miss | W91-77 | 18-4 | .818 | #16 | SEC Network | SJB Pavilion · Oxford, MS |
| 23 | Wed Feb 7 | vs#16Alabama | W99-81 | 19-4 | .826 | #12 | ESPN2 | Neville Arena · Auburn, AL |
| 24 | Sat Feb 10 | at Florida | L65-81 | 19-5 | .792 | #12 | SEC Network | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 25 | Wed Feb 14 | vs #11South Carolina | W101-61 | 20-5 | .800 | #13 | SEC Network | Neville Arena · Auburn, AL |
| 26 | Sat Feb 17 | vs #22Kentucky | L59-70 | 20-6 | .769 | #13 | ESPN | Neville Arena · Auburn, AL |
| 27 | Sat Feb 24 | at Georgia | W97-76 | 21-6 | .778 | #14 | SEC Network | Stegeman Coliseum · Athens, GA |
| 28 | Wed Feb 28 | at #4Tennessee | L84-92 | 21-7 | .750 | #11 | ESPN2 | Thompson-Boling Arena · Knoxville, TN |
| 29 | Sat Mar 2 | vsMississippi St | W78-63 | 22-7 | .759 | #11 | ESPN2 | Neville Arena · Auburn, AL |
| 30 | Tue Mar 5 | at Missouri | W101-74 | 23-7 | .767 | #13 | SEC Network | Mizzou Arena · Columbia, MO |
| 31 | Sat Mar 9 | vsGeorgia | W92-78 | 24-7 | .774 | #13 | SEC Network | Neville Arena · Auburn, AL |
| 32 | Fri Mar 15 | vs#15South Carolina | W86-55 | 25-7 | .781 | #12 | ESPN | Neville Arena · Auburn, AL |
| 33 | Sat Mar 16 | vsMississippi St | W73-66 | 26-7 | .788 | #12 | ESPN | Neville Arena · Auburn, AL |
| 34 | Sun Mar 17 | vsFlorida | W86-67 | 27-7 | .794 | #12 | ESPN | Neville Arena · Auburn, AL |
| 35 | Fri Mar 22 | vs #13Yale | L76-78 | 27-8 | .771 | #4 | TNT | Neville Arena · Auburn, AL |
