| 1 | Tue Nov 5 | vs Georgia So | W83-74 | 1-0 | 1.000 | #24 | SEC Network | Neville Arena · Auburn, AL |
| 2 | Fri Nov 8 | atDavidson | W76-66 | 2-0 | 1.000 | - | CBSSN | Alumni Hall (Navy) · Annapolis, MD |
| 3 | Tue Nov 12 | atSouth Alabama | W70-69 | 3-0 | 1.000 | #22 | | Mitchell Center · Mobile, AL |
| 4 | Fri Nov 15 | vsCSU Northridge | W116-70 | 4-0 | 1.000 | - | SEC Network | Neville Arena · Auburn, AL |
| 5 | Mon Nov 18 | vsColgate | W91-62 | 5-0 | 1.000 | - | SEC Network | Neville Arena · Auburn, AL |
| 6 | Mon Nov 25 | atNew Mexico | W84-59 | 6-0 | 1.000 | - | ESPNEWS | The Pit · Albuquerque, NM |
| 7 | Tue Nov 26 | atRichmond | W79-65 | 7-0 | 1.000 | - | ESPN2 | Robins Center · Richmond, VA |
| 8 | Thu Dec 5 | vsFurman | W81-78 (OT) | 8-0 | 1.000 | #14 | SEC Network | Neville Arena · Auburn, AL |
| 9 | Sat Dec 14 | vsSaint Louis | W67-61 | 9-0 | 1.000 | - | ESPN2 | Neville Arena · Auburn, AL |
| 10 | Thu Dec 19 | vsNC State | W79-73 | 10-0 | 1.000 | #12 | ESPN2 | Neville Arena · Auburn, AL |
| 11 | Sat Dec 21 | vsLehigh | W74-51 | 11-0 | 1.000 | #12 | SEC Network | Neville Arena · Auburn, AL |
| 12 | Sun Dec 29 | vsLipscomb | W86-59 | 12-0 | 1.000 | #8 | SEC Network | Neville Arena · Auburn, AL |
| 13 | Sat Jan 4 | atMississippi St | W80-68 | 13-0 | 1.000 | #8 | SEC Network | Humphrey Coliseum · Starkville, MS |
| 14 | Wed Jan 8 | vsVanderbilt | W83-79 | 14-0 | 1.000 | #5 | SEC Network | Neville Arena · Auburn, AL |
| 15 | Sat Jan 11 | vsGeorgia | W82-60 | 15-0 | 1.000 | #5 | ESPNEWS | Neville Arena · Auburn, AL |
| 16 | Wed Jan 15 | atAlabama | L64-83 | 15-1 | .938 | #4 | ESPN2 | Coleman Coliseum · Tuscaloosa, AL |
| 17 | Sat Jan 18 | atFlorida | L47-69 | 15-2 | .882 | #4 | CBS | O'Connell Center · Gainesville, FL |
| 18 | Wed Jan 22 | vsSouth Carolina | W80-67 | 16-2 | .889 | #16 | ESPNU | Neville Arena · Auburn, AL |
| 19 | Sat Jan 25 | vsIowa State | W80-76 | 17-2 | .895 | - | ESPNU | Neville Arena · Auburn, AL |
| 20 | Tue Jan 28 | atOle Miss | W83-82 (2OT) | 18-2 | .900 | #17 | ESPNU | SJB Pavilion · Oxford, MS |
| 21 | Sat Feb 1 | vs13Kentucky | W75-66 | 19-2 | .905 | #17 | ESPN | Neville Arena · Auburn, AL |
| 22 | Tue Feb 4 | atArkansas | W79-76 (OT) | 20-2 | .909 | #11 | SEC Network | Bud Walton Arena · Fayetteville, AR |
| 23 | Sat Feb 8 | vs18LSU | W91-90 (OT) | 21-2 | .913 | #11 | ESPN | Neville Arena · Auburn, AL |
| 24 | Wed Feb 12 | vsAlabama | W95-91 (OT) | 22-2 | .917 | #11 | ESPN2 | Neville Arena · Auburn, AL |
| 25 | Sat Feb 15 | atMissouri | L73-85 | 22-3 | .880 | #11 | ESPN2 | Mizzou Arena · Columbia, MO |
| 26 | Wed Feb 19 | atGeorgia | L55-65 | 22-4 | .846 | #13 | ESPN2 | Stegeman Coliseum · Athens, GA |
| 27 | Sat Feb 22 | vsTennessee | W73-66 | 23-4 | .852 | #13 | CBS | Neville Arena · Auburn, AL |
| 28 | Tue Feb 25 | vsOle Miss | W67-58 | 24-4 | .857 | #15 | SEC Network | Neville Arena · Auburn, AL |
| 29 | Sat Feb 29 | at8Kentucky | L66-73 | 24-5 | .828 | #15 | CBS | Rupp Arena · Lexington, KY |
| 30 | Wed Mar 4 | vsTexas A&M | L75-78 | 24-6 | .800 | #17 | ESPN2 | Neville Arena · Auburn, AL |
| 31 | Sat Mar 7 | atTennessee | W85-63 | 25-6 | .806 | #17 | ESPN2 | Thompson-Boling Arena · Knoxville, TN |
