| 1 | Tue Nov 9 | vs Morehead St | W77-54 | 1-0 | 1.000 | #22 | | Neville Arena · Auburn, AL |
| 2 | Fri Nov 12 | vs UL Monroe | W93-65 | 2-0 | 1.000 | #22 | | Neville Arena · Auburn, AL |
| 3 | Fri Nov 19 | at South Florida | W58-52 | 3-0 | 1.000 | #21 | | Yuengling Center · Tampa, FL |
| 4 | Wed Nov 24 | vs UConn | L109-115 (2OT) | 3-1 | .750 | - | ESPN | Neville Arena · Auburn, AL |
| 5 | Thu Nov 25 | at Loyola Chicago | W62-53 | 4-1 | .800 | - | ESPN2 | Joseph J. Gentile Arena · Chicago, IL |
| 6 | Fri Nov 26 | vs Syracuse | W89-68 | 5-1 | .833 | - | ESPN2 | Neville Arena · Auburn, AL |
| 7 | Wed Dec 1 | vs UCF | W85-68 | 6-1 | .857 | #21 | | Neville Arena · Auburn, AL |
| 8 | Sat Dec 4 | vs Yale | W86-64 | 7-1 | .875 | #21 | ESPNU | Neville Arena · Auburn, AL |
| 9 | Sat Dec 11 | vs Nebraska | W99-68 | 8-1 | .889 | - | ESPN2 | Neville Arena · Auburn, AL |
| 10 | Tue Dec 14 | vs North Alabama | W70-44 | 9-1 | .900 | #13 | SEC Network | Neville Arena · Auburn, AL |
| 11 | Sat Dec 18 | at Saint Louis | W74-70 | 10-1 | .909 | #13 | CBS | Chaifetz Arena · St. Louis, MO |
| 12 | Wed Dec 22 | vs Murray St | W71-58 | 11-1 | .917 | #12 | SEC Network | Neville Arena · Auburn, AL |
| 13 | Wed Dec 29 | vs #16LSU | W70-55 | 12-1 | .923 | #11 | ESPN2 | Neville Arena · Auburn, AL |
| 14 | Tue Jan 4 | at South Carolina | W81-66 | 13-1 | .929 | #9 | SEC Network | Colonial Life Arena · Columbia, SC |
| 15 | Sat Jan 8 | vs Florida | W85-73 | 14-1 | .933 | #9 | ESPN2 | Neville Arena · Auburn, AL |
| 16 | Tue Jan 11 | at #24Alabama | W81-77 | 15-1 | .938 | #4 | ESPN | Coleman Coliseum · Tuscaloosa, AL |
| 17 | Sat Jan 15 | at Ole Miss | W80-71 | 16-1 | .941 | #4 | SEC Network | SJB Pavilion · Oxford, MS |
| 18 | Wed Jan 19 | vs Georgia | W83-60 | 17-1 | .944 | #2 | ESPNU | Neville Arena · Auburn, AL |
| 19 | Sat Jan 22 | vs #12Kentucky | W80-71 | 18-1 | .947 | #2 | CBS | Neville Arena · Auburn, AL |
| 20 | Tue Jan 25 | at Missouri | W55-54 | 19-1 | .950 | #1 | SEC Network | Mizzou Arena · Columbia, MO |
| 21 | Sat Jan 29 | vs Oklahoma | W86-68 | 20-1 | .952 | - | ESPN | Neville Arena · Auburn, AL |
| 22 | Tue Feb 1 | vsAlabama | W100-81 | 21-1 | .955 | #1 | ESPN | Neville Arena · Auburn, AL |
| 23 | Sat Feb 5 | atGeorgia | W74-72 | 22-1 | .957 | #1 | SEC Network | Stegeman Coliseum · Athens, GA |
| 24 | Tue Feb 8 | at Arkansas | L76-80 (OT) | 22-2 | .917 | #1 | ESPN2 | Bud Walton Arena · Fayetteville, AR |
| 25 | Sat Feb 12 | vs Texas A&M | W75-58 | 23-2 | .920 | #1 | ESPN | Neville Arena · Auburn, AL |
| 26 | Wed Feb 16 | vs Vanderbilt | W94-80 | 24-2 | .923 | #2 | SEC Network | Neville Arena · Auburn, AL |
| 27 | Sat Feb 19 | atFlorida | L62-63 | 24-3 | .889 | #2 | ESPN | Exactech Arena at Stephen C. O'Connell Center · Gainesville, FL |
| 28 | Wed Feb 23 | vsOle Miss | W77-64 | 25-3 | .893 | #3 | SEC Network | Neville Arena · Auburn, AL |
| 29 | Sat Feb 26 | at #17Tennessee | L62-67 | 25-4 | .862 | #3 | ESPN | Thompson-Boling Arena · Knoxville, TN |
| 30 | Wed Mar 2 | at Mississippi St | W81-68 (OT) | 26-4 | .867 | #5 | SEC Network | Humphrey Coliseum · Starkville, MS |
| 31 | Sat Mar 5 | vsSouth Carolina | W82-71 | 27-4 | .871 | #5 | SEC Network | Neville Arena · Auburn, AL |
| 32 | Fri Mar 11 | vsTexas A&M | L62-67 | 27-5 | .844 | - | ESPN | Neville Arena · Auburn, AL |
| 33 | Fri Mar 18 | vs #15J'Ville St | W80-61 | 28-5 | .848 | #2 | truTV | Neville Arena · Auburn, AL |
| 34 | Sun Mar 20 | vs #10Miami | L61-79 | 28-6 | .824 | #2 | truTV | Neville Arena · Auburn, AL |
