| 1 | Mon Nov 3 | at Northeastern | 7:30 PM | 17-15 | .531 | - | | Matthews Arena · Boston, MA |
| 2 | Fri Nov 7 | atNorthwestern | TBD | 17-16 | .515 | - | Peacock | Welsh-Ryan Arena · Evanston, IL |
| 3 | Wed Nov 12 | vsBrown | TBD | 14-13 | .519 | - | ESPN+ | Case Gym · Boston, MA |
| 4 | Sat Nov 15 | vsMerrimack | TBD | 18-15 | .545 | - | ESPN+ | Case Gym · Boston, MA |
| 5 | Tue Nov 18 | atColumbia | 7:00 PM | 12-15 | .444 | - | ESPN+ | Francis S. Levien Gymnasium · New York, NY |
| 6 | Sat Nov 22 | vsHarvard | 1:30 PM | 12-15 | .444 | - | | Case Gym · Boston, MA |
| 7 | Tue Nov 25 | atPenn State | 7:00 PM | 16-15 | .516 | - | Peacock | Bryce Jordan Center · University Park, PA |
| 8 | Sat Nov 29 | atN Kentucky | 1:00 PM | 17-16 | .515 | - | ESPN+ | Truist Arena · Highland Heights, KY |
| 9 | Wed Dec 3 | vsTBD | TBD | 0-0 | .000 | - | | Case Gym · Boston, MA |
| 10 | Sat Dec 6 | atNew Hampshire | 7:00 PM | 8-24 | .250 | - | | Lundholm Gymnasium · Durham, NH |
| 11 | Wed Dec 10 | vsMaine | TBD | 20-14 | .588 | - | | Case Gym · Boston, MA |
| 12 | Sat Dec 13 | atDartmouth | 2:00 PM | 14-14 | .500 | - | | Edward Leede Arena · Hanover, NH |
| 13 | Sun Dec 21 | vsUMass Lowell | TBD | 17-15 | .531 | - | | Case Gym · Boston, MA |
| 14 | Wed Dec 31 | atNavy | TBD | 15-19 | .441 | - | | Alumni Hall (Navy) · Annapolis, MD |
| 15 | Sat Jan 3 | vsAmerican | 1:00 PM | 22-13 | .629 | - | | Case Gym · Boston, MA |
| 16 | Wed Jan 7 | atLafayette | 7:00 PM | 13-20 | .394 | - | | Kirby Sports Center · Easton, PA |
| 17 | Sat Jan 10 | vsArmy | TBD | 17-16 | .515 | - | | Case Gym · Boston, MA |
| 18 | Wed Jan 14 | vsLehigh | TBD | 11-19 | .367 | - | | Case Gym · Boston, MA |
| 19 | Sat Jan 17 | atLoyola MD | 1:00 PM | 12-19 | .387 | - | | Reitz Arena · Baltimore, MD |
| 20 | Wed Jan 21 | vsLafayette | 6:00 PM | 13-20 | .394 | - | | Case Gym · Boston, MA |
| 21 | Sat Jan 24 | atColgate | 2:00 PM | 14-19 | .424 | - | | Cotterell Court · Hamilton, NY |
| 22 | Wed Jan 28 | vsNavy | TBD | 15-19 | .441 | - | | Case Gym · Boston, MA |
| 23 | Sat Jan 31 | atBucknell | 2:00 PM | 18-15 | .545 | - | | Sojka Pavilion · Lewisburg, PA |
| 24 | Mon Feb 2 | atHoly Cross | TBD | 13-19 | .406 | - | | Hart Center · Worcester, MA |
| 25 | Sat Feb 7 | vsLoyola MD | TBD | 12-19 | .387 | - | | Case Gym · Boston, MA |
| 26 | Wed Feb 11 | atArmy | TBD | 17-16 | .515 | - | | Christl Arena · West Point, NY |
| 27 | Sat Feb 14 | vsBucknell | TBD | 18-15 | .545 | - | | Case Gym · Boston, MA |
| 28 | Mon Feb 16 | vsColgate | TBD | 14-19 | .424 | - | | Case Gym · Boston, MA |
| 29 | Sat Feb 21 | atLehigh | TBD | 11-19 | .367 | - | | Stabler Arena · Bethlehem, PA |
| 30 | Wed Feb 25 | vsHoly Cross | TBD | 13-19 | .406 | - | | Case Gym · Boston, MA |
| 31 | Sat Feb 28 | atAmerican | 2:00 PM | 22-13 | .629 | - | | Bender Arena · Washington, D.C. |
