| 1 | Tue Nov 9 | vs TBD | W118-71 | 1-0 | 1.000 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 2 | Fri Nov 12 | at Ole Miss | L68-93 | 1-1 | .500 | - | | SJB Pavilion · Oxford, MS |
| 3 | Wed Nov 17 | at Wake Forest | L59-95 | 1-2 | .333 | - | | Lawrence Joel Veterans Memorial Coliseum · Winston-Salem, NC |
| 4 | Sat Nov 20 | vsTBD | W119-63 | 2-2 | .500 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 5 | Mon Nov 22 | at Georgia Tech | L70-85 | 2-3 | .400 | - | ACC Network | McCamish Pavilion · Atlanta, GA |
| 6 | Fri Nov 26 | at Clemson | L59-91 | 2-4 | .333 | - | | Littlejohn Coliseum · Clemson, SC |
| 7 | Sun Nov 28 | at Kennesaw St | L52-89 | 2-5 | .286 | - | | KSU Convocation Center · Kennesaw, GA |
| 8 | Thu Dec 2 | vs Jacksonville | L56-67 | 2-6 | .250 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 9 | Sun Dec 5 | at Tarleton | W59-57 | 3-6 | .333 | - | | placeholder · sf, ca |
| 10 | Thu Dec 16 | vs Tennessee St | L75-78 | 3-7 | .300 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 11 | Mon Dec 20 | vs Manhattan | L75-99 | 3-8 | .273 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 12 | Tue Dec 21 | vs SC State | L65-75 | 3-9 | .250 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 13 | Sun Jan 2 | vsTBD | PPD | 6-25 | .194 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 14 | Wed Jan 5 | vs Gardner-Webb | L63-88 | 3-10 | .231 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 15 | Sat Jan 8 | at UNC Asheville | L59-82 | 3-11 | .214 | - | | Kimmel Arena · Asheville, NC |
| 16 | Wed Jan 12 | at Campbell | L52-67 | 3-12 | .200 | - | | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 17 | Sat Jan 15 | vs Winthrop | L65-70 | 3-13 | .188 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 18 | Wed Jan 19 | vs High Point | W70-66 | 4-13 | .235 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 19 | Sat Jan 22 | at SC Upstate | L57-70 | 4-14 | .222 | - | | G.B. Hodge Center · Spartanburg, SC |
| 20 | Wed Jan 26 | vs Presbyterian | L61-62 | 4-15 | .211 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 21 | Sat Jan 29 | vs Hampton | L74-78 | 4-16 | .200 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 22 | Wed Feb 2 | at Radford | L52-64 | 4-17 | .190 | - | | Donald N. Dedmon Center · Radford, VA |
| 23 | Sat Feb 5 | vs Longwood | L67-69 | 4-18 | .182 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 24 | Mon Feb 7 | vsTBD | W97-60 | 5-18 | .217 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 25 | Wed Feb 9 | at NC A&T | L51-62 | 5-19 | .208 | - | | Corbett Sports Center · Greensboro, NC |
| 26 | Sat Feb 12 | atGardner-Webb | L65-82 | 5-20 | .200 | - | | Paul Porter Arena · Boiling Springs, NC |
| 27 | Wed Feb 16 | vsUNC Asheville | L66-85 | 5-21 | .192 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 28 | Sat Feb 19 | vsSC Upstate | L73-78 (OT) | 5-22 | .185 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 29 | Wed Feb 23 | atPresbyterian | L48-68 | 5-23 | .179 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 30 | Sat Feb 26 | atWinthrop | L86-92 | 5-24 | .172 | - | | Winthrop Coliseum · Rock Hill, SC |
| 31 | Wed Mar 2 | atUNC Asheville | W79-78 | 6-24 | .200 | - | | Kimmel Arena · Asheville, NC |
| 32 | Fri Mar 4 | atSC Upstate | L62-72 | 6-25 | .194 | - | | G.B. Hodge Center · Spartanburg, SC |
