| 1 | Tue Nov 5 | vs TBD | W99-71 | 1-0 | 1.000 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 2 | Fri Nov 8 | at NC A&T | L49-63 | 1-1 | .500 | - | | Corbett Sports Center · Greensboro, NC |
| 3 | Tue Nov 12 | vs Furman | L47-91 | 1-2 | .333 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 4 | Sat Nov 16 | at Dayton | L61-90 | 1-3 | .250 | - | | UD Arena · Dayton, OH |
| 5 | Mon Nov 18 | at Michigan St | L46-94 | 1-4 | .200 | - | BTN | Breslin Center · East Lansing, MI |
| 6 | Sat Nov 23 | vs Southern Utah | L45-80 | 1-5 | .167 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 7 | Sun Nov 24 | vs Delaware St | W71-61 | 2-5 | .286 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 8 | Tue Dec 3 | at Missouri | W68-60 | 3-5 | .375 | - | | Mizzou Arena · Columbia, MO |
| 9 | Sat Dec 7 | vs NC Central | W58-53 | 4-5 | .444 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 10 | Mon Dec 16 | at JMU | L60-81 | 4-6 | .400 | - | | Atlantic Union Bank Center · Harrisonburg, VA |
| 11 | Sat Dec 21 | at E Kentucky | W76-69 | 5-6 | .455 | - | | McBrayer Arena · Richmond, KY |
| 12 | Sat Dec 28 | vsTBD | W108-52 | 6-6 | .500 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 13 | Thu Jan 2 | vs SC Upstate | W89-75 | 7-6 | .538 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 14 | Sat Jan 4 | at Hampton | L85-92 | 7-7 | .500 | - | | Convocation Center (VA) · Hampton, VA |
| 15 | Wed Jan 8 | vs Longwood | L56-74 | 7-8 | .467 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 16 | Sat Jan 11 | vs UNC Asheville | L69-71 | 7-9 | .438 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 17 | Thu Jan 16 | at Campbell | W77-62 | 8-9 | .471 | - | ESPNU | John W. Pope Jr. Convocation Center · Buies Creek, NC |
| 18 | Sat Jan 18 | at High Point | W79-60 | 9-9 | .500 | - | | Nido and Mariana Qubein Arena · High Point, NC |
| 19 | Thu Jan 23 | vs Presbyterian | W74-66 | 10-9 | .526 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 20 | Sat Jan 25 | at Gardner-Webb | W92-83 (2OT) | 11-9 | .550 | - | | Paul Porter Arena · Boiling Springs, NC |
| 21 | Thu Jan 30 | vs Winthrop | L60-77 | 11-10 | .524 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 22 | Sat Feb 1 | at Radford | L74-77 (OT) | 11-11 | .500 | - | | Donald N. Dedmon Center · Radford, VA |
| 23 | Thu Feb 6 | atLongwood | L63-71 | 11-12 | .478 | - | | Willett Hall · Farmville, VA |
| 24 | Sat Feb 8 | vsHampton | W85-72 | 12-12 | .500 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 25 | Mon Feb 10 | atSC Upstate | L52-66 | 12-13 | .480 | - | | G.B. Hodge Center · Spartanburg, SC |
| 26 | Thu Feb 13 | vsHigh Point | W66-63 | 13-13 | .500 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 27 | Sat Feb 15 | atUNC Asheville | L75-79 | 13-14 | .481 | - | | Kimmel Arena · Asheville, NC |
| 28 | Thu Feb 20 | vsCampbell | L51-66 | 13-15 | .464 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 29 | Thu Feb 27 | vsGardner-Webb | L74-83 | 13-16 | .448 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 30 | Sat Feb 29 | atPresbyterian | L65-76 | 13-17 | .433 | - | | Ross E. Templeton P.E. Center · Clinton, SC |
| 31 | Tue Mar 3 | vsPresbyterian | W81-64 | 14-17 | .452 | - | | Buccaneer Fieldhouse · Charleston, SC |
| 32 | Thu Mar 5 | atRadford | L48-62 | 14-18 | .438 | - | | Donald N. Dedmon Center · Radford, VA |
