| 1 | Tue Nov 9 | vs Sacred Heart | L81-86 (OT) | 0-1 | .000 | - | | Tom Gola Arena · Philadelphia, PA |
| 2 | Sat Nov 13 | vsAlbany | W67-64 | 1-1 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 3 | Wed Nov 17 | atDelaware | L82-85 (OT) | 1-2 | .333 | - | | Bob Carpenter Center · Newark, DE |
| 4 | Sat Nov 20 | vsArmy | W61-58 | 2-2 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 5 | Sun Nov 28 | vs7Villanova | L46-72 | 2-3 | .400 | - | ESPN2 | The Palestra · Philadelphia, PA |
| 6 | Wed Dec 1 | atTemple | L57-73 | 2-4 | .333 | - | | Liacouras Center · Philadelphia, PA |
| 7 | Sat Dec 4 | vsHoly Cross | W84-65 | 3-4 | .429 | - | | Tom Gola Arena · Philadelphia, PA |
| 8 | Tue Dec 7 | vsFairleigh | W81-55 | 4-4 | .500 | - | | Tom Gola Arena · Philadelphia, PA |
| 9 | Sat Dec 11 | vsPenn | W76-74 | 5-4 | .556 | - | | Tom Gola Arena · Philadelphia, PA |
| 10 | Sat Dec 18 | atBucknell | L70-82 | 5-5 | .500 | - | | Sojka Pavilion · Lewisburg, PA |
| 12 | Thu Dec 30 | vsFordham | L61-69 | 5-6 | .455 | - | | Tom Gola Arena · Philadelphia, PA |
| 13 | Wed Jan 5 | atSaint Louis | PPD | 11-19 | .367 | - | | Chaifetz Arena · St. Louis, MO |
| 14 | Sat Jan 8 | vsVCU | L66-85 | 5-7 | .417 | - | | Tom Gola Arena · Philadelphia, PA |
| 15 | Tue Jan 11 | vsSt Bonaventure | L76-80 (OT) | 5-8 | .385 | - | | Tom Gola Arena · Philadelphia, PA |
| 16 | Mon Jan 17 | atSaint Joseph's | W75-64 | 6-8 | .429 | - | CBSSN | Michael J. Hagan '85 Arena · Philadelphia, PA |
| 17 | Wed Jan 19 | atRhode Island | L54-56 | 6-9 | .400 | - | | Ryan Center · Kingston, RI |
| 18 | Sat Jan 22 | vsRichmond | L56-64 | 6-10 | .375 | - | | Tom Gola Arena · Philadelphia, PA |
| 19 | Wed Jan 26 | vsUMass | L71-77 | 6-11 | .353 | - | | Tom Gola Arena · Philadelphia, PA |
| 20 | Sat Jan 29 | at25Davidson | L69-77 | 6-12 | .333 | - | USA Net | John M. Belk Arena · Davidson, NC |
| 21 | Wed Feb 2 | atG Washington | L87-89 | 6-13 | .316 | - | | Charles E. Smith Center · Washington, D.C. |
| 22 | Sat Feb 5 | vsGeorge Mason | W83-78 | 7-13 | .350 | - | | Tom Gola Arena · Philadelphia, PA |
| 23 | Tue Feb 8 | vsSaint Louis | L57-75 | 7-14 | .333 | - | | Tom Gola Arena · Philadelphia, PA |
| 24 | Sat Feb 12 | atRichmond | L63-77 | 7-15 | .318 | - | | Robins Center · Richmond, VA |
| 25 | Wed Feb 16 | atSaint Louis | L64-90 | 7-16 | .304 | - | | Chaifetz Arena · St. Louis, MO |
| 26 | Sat Feb 19 | atUMass | L74-80 | 7-17 | .292 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 27 | Wed Feb 23 | atFordham | L54-60 | 7-18 | .280 | - | | Rose Hill Gymnasium · Bronx, NY |
| 28 | Sat Feb 26 | vsDayton | W62-60 | 8-18 | .308 | - | | Tom Gola Arena · Philadelphia, PA |
| 29 | Wed Mar 2 | vsSaint Joseph's | W49-48 | 9-18 | .333 | - | | Tom Gola Arena · Philadelphia, PA |
| 30 | Sat Mar 5 | atDuquesne | W85-76 | 10-18 | .357 | - | | UPMC Cooper Fieldhouse · Pittsburgh, PA |
| 31 | Wed Mar 9 | vsSaint Joseph's | W63-56 | 11-18 | .379 | - | | Capital One Arena · Washington, D.C. |
| 32 | Thu Mar 10 | atSaint Louis | L51-71 | 11-19 | .367 | - | USA Net | Capital One Arena · Washington, D.C. |
