| 1 | Mon Nov 7 | vs Columbia | W75-35 | 1-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 2 | Thu Nov 10 | vs Sacred Heart | W88-50 | 2-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 3 | Sat Nov 12 | vs UMass Lowell | W73-65 | 3-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 4 | Fri Nov 18 | vs Temple | L66-72 | 3-1 | .750 | - | ESPNU | Jersey Mike’s Arena · Piscataway, NJ |
| 5 | Tue Nov 22 | vs Rider | W76-46 | 4-1 | .800 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 6 | Sat Nov 26 | vs C Connecticut | W83-49 | 5-1 | .833 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 7 | Wed Nov 30 | at Miami | L61-68 | 5-2 | .714 | - | ESPNU | Watsco Center · Coral Gables, FL |
| 8 | Sat Dec 3 | vs #10Indiana | W63-48 | 6-2 | .750 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 9 | Thu Dec 8 | at #25Ohio State | L66-67 | 6-3 | .667 | - | ESPN2 | Value City Arena · Columbus, OH |
| 10 | Sun Dec 11 | vs Seton Hall | L43-45 | 6-4 | .600 | - | FS1 | Jersey Mike’s Arena · Piscataway, NJ |
| 11 | Sat Dec 17 | vs Wake Forest | W81-57 | 7-4 | .636 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 12 | Fri Dec 23 | vs Bucknell | W85-50 | 8-4 | .667 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 13 | Fri Dec 30 | vs Coppin St | W90-57 | 9-4 | .692 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 14 | Mon Jan 2 | at #1Purdue | W65-64 | 10-4 | .714 | - | BTN | Mackey Arena · West Lafayette, IN |
| 15 | Thu Jan 5 | vs Maryland | W64-50 | 11-4 | .733 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 16 | Sun Jan 8 | vs Iowa | L65-76 | 11-5 | .688 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 17 | Wed Jan 11 | at Northwestern | W65-62 | 12-5 | .706 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 18 | Sun Jan 15 | vsOhio State | W68-64 (OT) | 13-5 | .722 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 19 | Thu Jan 19 | at Michigan St | L57-70 | 13-6 | .684 | #23 | FS1 | Breslin Center · East Lansing, MI |
| 20 | Tue Jan 24 | vs Penn State | W65-45 | 14-6 | .700 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 21 | Sun Jan 29 | atIowa | L82-93 | 14-7 | .667 | - | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 22 | Wed Feb 1 | vs Minnesota | W90-55 | 15-7 | .682 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 23 | Sat Feb 4 | vsMichigan St | W61-55 | 16-7 | .696 | - | FOX | Jersey Mike’s Arena · Piscataway, NJ |
| 24 | Tue Feb 7 | at#18Indiana | L60-66 | 16-8 | .667 | #24 | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 25 | Sat Feb 11 | at Illinois | L60-69 | 16-9 | .640 | #24 | FS1 | State Farm Center · Champaign, IL |
| 26 | Tue Feb 14 | vs Nebraska | L72-82 | 16-10 | .615 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 27 | Sat Feb 18 | at Wisconsin | W58-57 | 17-10 | .630 | - | BTN | Kohl Center · Madison, WI |
| 28 | Thu Feb 23 | vs Michigan | L45-58 | 17-11 | .607 | - | FS1 | Jersey Mike’s Arena · Piscataway, NJ |
| 29 | Sun Feb 26 | atPenn State | W59-56 | 18-11 | .621 | - | BTN | Bryce Jordan Center · University Park, PA |
| 30 | Thu Mar 2 | atMinnesota | L74-75 | 18-12 | .600 | - | FS1 | Williams Arena · Minneapolis, MN |
| 31 | Sun Mar 5 | vsNorthwestern | L53-65 | 18-13 | .581 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 32 | Thu Mar 9 | atMichigan | W62-50 | 19-13 | .594 | - | BTN | Crisler Center · Ann Arbor, MI |
| 33 | Fri Mar 10 | atPurdue | L65-70 | 19-14 | .576 | - | BTN | Mackey Arena · West Lafayette, IN |
| 34 | Tue Mar 14 | vs Hofstra | L86-88 (OT) | 19-15 | .559 | - | ESPNU | Jersey Mike’s Arena · Piscataway, NJ |
