| 1 | Wed Nov 10 | vs Lehigh | W73-70 (OT) | 1-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 2 | Sat Nov 13 | vsMerrimack | W48-35 | 2-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 3 | Tue Nov 16 | vsNJIT | W75-61 | 3-0 | 1.000 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 4 | Thu Nov 18 | atDePaul | L70-73 | 3-1 | .750 | - | FS1 | Wintrust Arena · Chicago, IL |
| 5 | Mon Nov 22 | vsLafayette | L51-53 | 3-2 | .600 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 6 | Sat Nov 27 | atUMass | L83-85 | 3-3 | .500 | - | | William D. Mullins Memorial Center · Amherst, MA |
| 7 | Tue Nov 30 | vsClemson | W74-64 | 4-3 | .571 | - | ESPN2 | Jersey Mike’s Arena · Piscataway, NJ |
| 8 | Fri Dec 3 | atIllinois | L51-86 | 4-4 | .500 | - | ESPN2 | State Farm Center · Champaign, IL |
| 9 | Thu Dec 9 | vs1Purdue | W70-68 | 5-4 | .556 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 10 | Sun Dec 12 | atSeton Hall | L63-77 | 5-5 | .500 | - | FS1 | Prudential Center · Newark, NJ |
| 12 | Thu Dec 23 | vsC Connecticut | PPD | 18-14 | .563 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 13 | Thu Dec 30 | vsMaine | W80-64 | 6-5 | .545 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 14 | Sat Jan 1 | vsC Connecticut | W79-48 | 7-5 | .583 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 15 | Tue Jan 4 | vsMichigan | W75-67 | 8-5 | .615 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 16 | Sat Jan 8 | vsNebraska | W93-65 | 9-5 | .643 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 17 | Tue Jan 11 | atPenn State | L49-66 | 9-6 | .600 | - | BTN | Bryce Jordan Center · University Park, PA |
| 18 | Sat Jan 15 | atMaryland | W70-59 | 10-6 | .625 | - | BTN | XFINITY Center · College Park, MD |
| 19 | Wed Jan 19 | vsIowa | W48-46 | 11-6 | .647 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 20 | Sat Jan 22 | atMinnesota | L65-68 | 11-7 | .611 | - | BTN | Williams Arena · Minneapolis, MN |
| 21 | Tue Jan 25 | vsMaryland | L60-68 | 11-8 | .579 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 22 | Sat Jan 29 | atNebraska | W63-61 | 12-8 | .600 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 23 | Tue Feb 1 | atNorthwestern | L78-79 (OT) | 12-9 | .571 | - | BTN | Welsh-Ryan Arena · Evanston, IL |
| 24 | Sat Feb 5 | vs13Michigan St | W84-63 | 13-9 | .591 | - | FS1 | Jersey Mike’s Arena · Piscataway, NJ |
| 25 | Wed Feb 9 | vs16Ohio State | W66-64 | 14-9 | .609 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 26 | Sat Feb 12 | at14Wisconsin | W73-65 | 15-9 | .625 | - | FS1 | Kohl Center · Madison, WI |
| 27 | Wed Feb 16 | vs12Illinois | W70-59 | 16-9 | .640 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 28 | Sun Feb 20 | at5Purdue | L72-84 | 16-10 | .615 | - | FS1 | Mackey Arena · West Lafayette, IN |
| 29 | Wed Feb 23 | atMichigan | L62-71 | 16-11 | .593 | - | BTN | Crisler Center · Ann Arbor, MI |
| 30 | Sat Feb 26 | vs13Wisconsin | L61-66 | 16-12 | .571 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 31 | Wed Mar 2 | atIndiana | W66-63 | 17-12 | .586 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 32 | Sun Mar 6 | vsPenn State | W59-58 | 18-12 | .600 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 33 | Fri Mar 11 | vsIowa | L74-84 | 18-13 | .581 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 33 | Wed Mar 16 | vs11Notre Dame | L87-89 (2OT) | 18-14 | .563 | #11 | truTV | UD Arena · Dayton, OH |
