| 1 | Thu Nov 7 | vs Bryant | W73-71 | 1-0 | 1.000 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 2 | Sun Nov 10 | vsNiagara | W86-39 | 2-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 3 | Wed Nov 13 | vsDrexel | W62-57 | 3-0 | 1.000 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 4 | Sat Nov 16 | vsSt Bonaventure | L74-80 | 3-1 | .750 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 5 | Wed Nov 20 | vsSF Austin | W69-57 | 4-1 | .800 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 6 | Tue Nov 26 | vsNJIT | W85-58 | 5-1 | .833 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 7 | Fri Nov 29 | vsUMass | W82-57 | 6-1 | .857 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 8 | Tue Dec 3 | atPitt | L60-71 | 6-2 | .750 | - | ESPNU | Petersen Events Center · Pittsburgh, PA |
| 9 | Sun Dec 8 | at#11Michigan St | L65-77 | 6-3 | .667 | - | BTN | Breslin Center · East Lansing, MI |
| 10 | Wed Dec 11 | vsWisconsin | W72-65 | 7-3 | .700 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 11 | Sat Dec 14 | vsSeton Hall | W68-48 | 8-3 | .727 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 12 | Sun Dec 22 | vsLafayette | W63-44 | 9-3 | .750 | - | ESPNU | Jersey Mike’s Arena · Piscataway, NJ |
| 13 | Mon Dec 30 | vsTBD | W94-49 | 10-3 | .769 | - | | Jersey Mike’s Arena · Piscataway, NJ |
| 14 | Fri Jan 3 | atNebraska | W79-62 | 11-3 | .786 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 15 | Tue Jan 7 | vs#20Penn State | W72-61 | 12-3 | .800 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 16 | Sat Jan 11 | atIllinois | L51-54 | 12-4 | .750 | - | BTN | State Farm Center · Champaign, IL |
| 17 | Wed Jan 15 | vsIndiana | W59-50 | 13-4 | .765 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 18 | Sun Jan 19 | vsMinnesota | W64-56 | 14-4 | .778 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 19 | Wed Jan 22 | at#19Iowa | L80-85 | 14-5 | .737 | #24 | BTN | Carver-Hawkeye Arena · Iowa City, IA |
| 20 | Sat Jan 25 | vsNebraska | W75-72 | 15-5 | .750 | #24 | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 21 | Tue Jan 28 | vsPurdue | W70-63 | 16-5 | .762 | #25 | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 22 | Sat Feb 1 | atMichigan | L63-69 | 16-6 | .727 | #25 | BTN | Crisler Center · Ann Arbor, MI |
| 23 | Tue Feb 4 | at#9Maryland | L51-56 | 16-7 | .696 | - | FS1 | XFINITY Center · College Park, MD |
| 24 | Sun Feb 9 | vsNorthwestern | W77-73 (OT) | 17-7 | .708 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 25 | Wed Feb 12 | atOhio State | L66-72 | 17-8 | .680 | - | BTN | Value City Arena · Columbus, OH |
| 26 | Sat Feb 15 | vs#22Illinois | W72-57 | 18-8 | .692 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 27 | Wed Feb 19 | vsMichigan | L52-60 | 18-9 | .667 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 28 | Sun Feb 23 | atWisconsin | L71-79 | 18-10 | .643 | - | BTN | Kohl Center · Madison, WI |
| 29 | Wed Feb 26 | at#16Penn State | L64-65 | 18-11 | .621 | - | BTN | Bryce Jordan Center · University Park, PA |
| 30 | Tue Mar 3 | vs#9Maryland | W78-67 | 19-11 | .633 | - | BTN | Jersey Mike’s Arena · Piscataway, NJ |
| 31 | Sat Mar 7 | atPurdue | W71-68 (OT) | 20-11 | .645 | - | BTN | Mackey Arena · West Lafayette, IN |
