| 3 | Tue Nov 11 | at Coast Car | 7:00 PM | 1-1 | .500 | - | ESPN+ | The HTC Center · Conway, SC |
| 4 | Sat Nov 15 | vsMercer | 2:00 PM | 1-1 | .500 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 5 | Tue Nov 18 | at#14Arkansas | 8:00 PM | 1-1 | .500 | - | SECN+ | Bud Walton Arena · Fayetteville, AR |
| 6 | Sun Nov 23 | atJackson St | TBD | 0-2 | .000 | - | | Lee E. Williams Athletic and Assembly Center · Jackson, MS |
| 7 | Tue Nov 25 | atNebraska | 8:30 PM | 2-0 | 1.000 | - | BTN | Pinnacle Bank Arena · Lincoln, NE |
| 8 | Sat Nov 29 | vsSC State | 4:00 PM | 0-2 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 9 | Tue Dec 2 | atLong Island | 7:30 PM | 1-1 | .500 | - | | Steinberg Wellness Center · Brooklyn, NY |
| 10 | Sat Dec 6 | vsCoast Car | 2:00 PM | 1-1 | .500 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 11 | Tue Dec 9 | vsTBD | 6:30 PM | 0-0 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 12 | Sat Dec 13 | vsTBD | 6:30 PM | 0-0 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 13 | Thu Dec 18 | atNorth Dakota | 8:00 PM | 0-2 | .000 | - | | Betty Engelstad Sioux Center · Grand Forks, ND |
| 14 | Sun Dec 21 | vsTBD | 12:00 PM | 0-0 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 15 | Sun Dec 28 | at#10Texas Tech | 2:00 PM | 2-0 | 1.000 | - | TNT | United Supermarkets Arena · Lubbock, TX |
| 16 | Wed Dec 31 | atLongwood | 3:00 PM | 1-1 | .500 | - | ESPN+ | Willett Hall · Farmville, VA |
| 17 | Sat Jan 3 | vsGardner-Webb | 4:00 PM | 0-2 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 18 | Wed Jan 7 | vsCharleston So | 6:30 PM | 1-1 | .500 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 19 | Sat Jan 10 | atSC Upstate | 2:00 PM | 2-1 | .667 | - | ESPN+ | G.B. Hodge Center · Spartanburg, SC |
| 20 | Wed Jan 14 | vsHigh Point | 6:30 PM | 2-0 | 1.000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 21 | Sat Jan 17 | atUNC Asheville | 2:00 PM | 0-2 | .000 | - | ESPN+ | Kimmel Arena · Asheville, NC |
| 22 | Wed Jan 21 | vsRadford | 6:30 PM | 2-0 | 1.000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 23 | Sat Jan 24 | atPresbyterian | 4:30 PM | 2-1 | .667 | - | ESPN+ | Ross E. Templeton P.E. Center · Clinton, SC |
| 24 | Sat Jan 31 | vsUNC Asheville | 2:00 PM | 0-2 | .000 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 25 | Wed Feb 4 | atRadford | 7:00 PM | 2-0 | 1.000 | - | ESPN+ | Donald N. Dedmon Center · Radford, VA |
| 26 | Sat Feb 7 | vsLongwood | 2:00 PM | 1-1 | .500 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 27 | Thu Feb 12 | atGardner-Webb | 7:00 PM | 0-2 | .000 | - | ESPN+ | Paul Porter Arena · Boiling Springs, NC |
| 28 | Thu Feb 19 | vsSC Upstate | 6:30 PM | 2-1 | .667 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
| 29 | Sat Feb 21 | atHigh Point | 4:00 PM | 2-0 | 1.000 | - | ESPN+ | Nido and Mariana Qubein Arena · High Point, NC |
| 30 | Thu Feb 26 | atCharleston So | 7:00 PM | 1-1 | .500 | - | ESPN+ | Buccaneer Fieldhouse · Charleston, SC |
| 31 | Sat Feb 28 | vsPresbyterian | 4:00 PM | 2-1 | .667 | - | ESPN+ | Winthrop Coliseum · Rock Hill, SC |
