| 1 | Wed Nov 9 | vs Davidson | L97-102 (2OT) | 0-1 | .000 | - | | Nutter Center · Dayton, OH |
| 2 | Sat Nov 12 | at Louisville | W73-72 | 1-1 | .500 | - | | KFC Yum! Center · Louisville, KY |
| 3 | Tue Nov 15 | vs Bowling Green | W80-71 | 2-1 | .667 | - | | Nutter Center · Dayton, OH |
| 4 | Thu Nov 17 | vs TBD | W99-56 | 3-1 | .750 | - | | Nutter Center · Dayton, OH |
| 5 | Mon Nov 21 | vs Abilene Chrstn | W77-61 | 4-1 | .800 | - | | Nutter Center · Dayton, OH |
| 6 | Tue Nov 22 | at UC Riverside | L65-70 | 4-2 | .667 | - | | SRC Arena · Riverside, CA |
| 7 | Wed Nov 23 | at Weber St | W87-65 | 5-2 | .714 | - | | Dee Events Center · Ogden, UT |
| 8 | Thu Dec 1 | vs Robert Morris | L59-80 | 5-3 | .625 | - | | Nutter Center · Dayton, OH |
| 9 | Sun Dec 4 | vs Youngstown St | L77-88 | 5-4 | .556 | - | | Nutter Center · Dayton, OH |
| 10 | Sat Dec 10 | at Western KY | L60-64 | 5-5 | .500 | - | | E. A. Diddle Arena · Bowling Green, KY |
| 11 | Wed Dec 14 | at Akron | L54-66 | 5-6 | .455 | - | | James A. Rhodes Arena · Akron, OH |
| 12 | Sat Dec 17 | vsTBD | W111-59 | 6-6 | .500 | - | | Nutter Center · Dayton, OH |
| 13 | Thu Dec 22 | at Miami OH | W88-80 | 7-6 | .538 | - | | Millett Hall · Oxford, OH |
| 14 | Thu Dec 29 | at N Kentucky | L64-78 | 7-7 | .500 | - | | Truist Arena · Highland Heights, KY |
| 15 | Mon Jan 2 | at IU Indy | W82-68 | 8-7 | .533 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 16 | Fri Jan 6 | vs Detroit Mercy | W90-85 | 9-7 | .563 | - | ESPN2 | Nutter Center · Dayton, OH |
| 17 | Sun Jan 8 | vs Oakland | L73-75 | 9-8 | .529 | - | | Nutter Center · Dayton, OH |
| 18 | Thu Jan 12 | at Green Bay | W99-67 | 10-8 | .556 | - | | Resch Center · Ashwaubenon, WI |
| 19 | Sat Jan 14 | at Milwaukee | W78-74 (OT) | 11-8 | .579 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 20 | Thu Jan 19 | vs Purdue FW | L80-88 | 11-9 | .550 | - | | Nutter Center · Dayton, OH |
| 21 | Sat Jan 21 | vs Cleveland St | L77-85 | 11-10 | .524 | - | | Nutter Center · Dayton, OH |
| 22 | Thu Jan 26 | vsMilwaukee | W93-86 | 12-10 | .545 | - | | Nutter Center · Dayton, OH |
| 23 | Sat Jan 28 | vsGreen Bay | W77-46 | 13-10 | .565 | - | | Nutter Center · Dayton, OH |
| 24 | Thu Feb 2 | atYoungstown St | L89-91 (3OT) | 13-11 | .542 | - | | Beeghly Center · Youngstown, OH |
| 25 | Sat Feb 4 | atRobert Morris | W82-67 | 14-11 | .560 | - | | UPMC Events Center · Moon Township, PA |
| 26 | Wed Feb 8 | vsIU Indy | W103-71 | 15-11 | .577 | - | | Nutter Center · Dayton, OH |
| 27 | Fri Feb 10 | vsN Kentucky | W83-65 | 16-11 | .593 | - | ESPNU | Nutter Center · Dayton, OH |
| 28 | Fri Feb 17 | atCleveland St | L68-85 | 16-12 | .571 | - | ESPNU | Wolstein Center · Cleveland, OH |
| 29 | Sun Feb 19 | atPurdue FW | L75-77 | 16-13 | .552 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 30 | Thu Feb 23 | atOakland | L68-75 | 16-14 | .533 | - | | Athletics Center O'rena · Rochester, MI |
| 31 | Sat Feb 25 | atDetroit Mercy | W82-71 | 17-14 | .548 | - | | Calihan Hall · Detroit, MI |
| 32 | Tue Feb 28 | vsGreen Bay | W77-57 | 18-14 | .563 | - | | Nutter Center · Dayton, OH |
| 33 | Thu Mar 2 | atMilwaukee | L70-87 | 18-15 | .545 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
