| 1 | Fri Nov 10 | at Colorado St | L77-105 | 0-1 | .000 | - | | Moby Arena · Fort Collins, CO |
| 2 | Tue Nov 14 | vs Toledo | L77-78 | 0-2 | .000 | - | | Nutter Center · Dayton, OH |
| 3 | Thu Nov 16 | at Indiana | L80-89 | 0-3 | .000 | - | BTN | Simon Skjodt Assembly Hall · Bloomington, IN |
| 4 | Mon Nov 20 | at Louisiana | W91-85 | 1-3 | .250 | - | | Cajundome · Lafayette, LA |
| 5 | Tue Nov 21 | vs Hofstra | L76-85 | 1-4 | .200 | - | | Nutter Center · Dayton, OH |
| 6 | Wed Nov 22 | at Illinois St | W74-49 | 2-4 | .333 | - | | Redbird Arena · Normal, IL |
| 7 | Wed Nov 29 | vs IU Indy | W103-74 | 3-4 | .429 | - | | Nutter Center · Dayton, OH |
| 8 | Sat Dec 2 | at Davidson | L73-82 | 3-5 | .375 | - | | John M. Belk Arena · Davidson, NC |
| 9 | Thu Dec 7 | vs TBD | W81-62 | 4-5 | .444 | - | | Nutter Center · Dayton, OH |
| 10 | Tue Dec 12 | vs Western KY | L84-91 | 4-6 | .400 | - | | Nutter Center · Dayton, OH |
| 11 | Tue Dec 19 | vs Miami OH | W92-82 | 5-6 | .455 | - | | Nutter Center · Dayton, OH |
| 12 | Fri Dec 22 | vsTBD | W101-54 | 6-6 | .500 | - | | Nutter Center · Dayton, OH |
| 13 | Fri Dec 29 | at Green Bay | L77-88 | 6-7 | .462 | - | | Resch Center · Ashwaubenon, WI |
| 14 | Sun Dec 31 | at Milwaukee | L83-91 | 6-8 | .429 | - | | UW-Milwaukee Panther Arena · Milwaukee, WI |
| 15 | Thu Jan 4 | vs Cleveland St | W82-70 | 7-8 | .467 | - | ESPN2 | Nutter Center · Dayton, OH |
| 16 | Sat Jan 6 | at Purdue FW | W106-98 | 8-8 | .500 | - | | Allen County War Memorial Coliseum · Fort Wayne, IN |
| 17 | Wed Jan 10 | at Robert Morris | W101-76 | 9-8 | .529 | - | | UPMC Events Center · Moon Township, PA |
| 18 | Fri Jan 12 | at Youngstown St | L71-81 | 9-9 | .500 | - | ESPN2 | Beeghly Center · Youngstown, OH |
| 19 | Thu Jan 18 | vsGreen Bay | L81-88 | 9-10 | .474 | - | | Nutter Center · Dayton, OH |
| 20 | Sat Jan 20 | vsMilwaukee | W95-81 | 10-10 | .500 | - | | Nutter Center · Dayton, OH |
| 21 | Thu Jan 25 | atCleveland St | W107-99 (OT) | 11-10 | .524 | - | | Wolstein Center · Cleveland, OH |
| 22 | Sun Jan 28 | atIU Indy | W83-76 | 12-10 | .545 | - | | Indiana Farmers Coliseum · Indianapolis, IN |
| 23 | Thu Feb 1 | vsYoungstown St | L77-88 | 12-11 | .522 | - | ESPNU | Nutter Center · Dayton, OH |
| 24 | Sun Feb 4 | at N Kentucky | W85-78 | 13-11 | .542 | - | | Truist Arena · Highland Heights, KY |
| 25 | Thu Feb 8 | vs Detroit Mercy | W92-85 | 14-11 | .560 | - | | Nutter Center · Dayton, OH |
| 26 | Sat Feb 10 | vs Oakland | L60-74 | 14-12 | .538 | - | | Nutter Center · Dayton, OH |
| 27 | Sat Feb 17 | vsRobert Morris | W101-71 | 15-12 | .556 | - | | Nutter Center · Dayton, OH |
| 28 | Thu Feb 22 | atDetroit Mercy | W93-78 | 16-12 | .571 | - | | Calihan Hall · Detroit, MI |
| 29 | Sun Feb 25 | atOakland | W96-75 | 17-12 | .586 | - | | Athletics Center O'rena · Rochester, MI |
| 30 | Wed Feb 28 | vsPurdue FW | L77-79 (OT) | 17-13 | .567 | - | | Nutter Center · Dayton, OH |
| 31 | Sat Mar 2 | vsN Kentucky | W94-88 | 18-13 | .581 | - | | Nutter Center · Dayton, OH |
| 32 | Thu Mar 7 | vsN Kentucky | L97-99 (OT) | 18-14 | .563 | - | | Nutter Center · Dayton, OH |
