| 3 | Sun Sep 22 | at Cardinals | 4:25 PM | 1-1 | .500 | State Farm Stadium · Glendale, AZ |
| 4 | Mon Sep 30 | vs Seahawks | 8:15 PM | 2-0 | 1.000 | Ford Field · Detroit, MI |
| 6 | Sun Oct 13 | at Cowboys | 4:25 PM | 1-1 | .500 | AT&T Stadium · Arlington, TX |
| 7 | Sun Oct 20 | at Vikings | 1:00 PM | 2-0 | 1.000 | U.S. Bank Stadium · Minneapolis, MN |
| 8 | Sun Oct 27 | vs Titans | 1:00 PM | 0-2 | .000 | Ford Field · Detroit, MI |
| 9 | Sun Nov 3 | at Packers | 4:25 PM | 1-1 | .500 | Lambeau Field · Green Bay, WI |
| 10 | Sun Nov 10 | at Texans | 8:20 PM | 2-0 | 1.000 | NRG Stadium · Houston, TX |
| 11 | Sun Nov 17 | vs Jaguars | 1:00 PM | 0-2 | .000 | Ford Field · Detroit, MI |
| 12 | Sun Nov 24 | at Colts | 1:00 PM | 0-2 | .000 | Lucas Oil Stadium · Indianapolis, IN |
| 13 | Thu Nov 28 | vs Bears | 12:30 PM | 1-1 | .500 | Ford Field · Detroit, MI |
| 14 | Thu Dec 5 | vsPackers | 8:15 PM | 1-1 | .500 | Ford Field · Detroit, MI |
| 15 | Sun Dec 15 | vs Bills | 4:25 PM | 2-0 | 1.000 | Ford Field · Detroit, MI |
| 16 | Sun Dec 22 | atBears | 1:00 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 17 | Mon Dec 30 | at 49ers | 8:15 PM | 1-1 | .500 | Levi's® Stadium · Santa Clara, CA |
| 18 | TBD | vsVikings | TBD | 2-0 | 1.000 | Ford Field · Detroit, MI |
Buccaneers
Rams