| 3 | Sun Sep 22 | at Colts | 1:00 PM | 0-2 | .000 | Lucas Oil Stadium · Indianapolis, IN |
| 4 | Sun Sep 29 | vs Rams | 1:00 PM | 0-2 | .000 | Soldier Field · Chicago, IL |
| 5 | Sun Oct 6 | vs Panthers | 1:00 PM | 0-2 | .000 | Soldier Field · Chicago, IL |
| 6 | Sun Oct 13 | vs Jaguars | 9:30 AM | 0-2 | .000 | Tottenham Hotspur Stadium · London, England |
| 8 | Sun Oct 27 | at Commanders | 1:00 PM | 1-1 | .500 | FedEx Field · North Englewood, MD |
| 9 | Sun Nov 3 | at Cardinals | 4:05 PM | 1-1 | .500 | State Farm Stadium · Glendale, AZ |
| 10 | Sun Nov 10 | vs Patriots | 1:00 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 11 | Sun Nov 17 | vs Packers | 1:00 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 12 | Sun Nov 24 | vs Vikings | 1:00 PM | 2-0 | 1.000 | Soldier Field · Chicago, IL |
| 13 | Thu Nov 28 | at Lions | 12:30 PM | 1-1 | .500 | Ford Field · Detroit, MI |
| 14 | Sun Dec 8 | at 49ers | 4:25 PM | 1-1 | .500 | Levi's® Stadium · Santa Clara, CA |
| 15 | Mon Dec 16 | atVikings | 8:00 PM | 2-0 | 1.000 | U.S. Bank Stadium · Minneapolis, MN |
| 16 | Sun Dec 22 | vsLions | 1:00 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 17 | Thu Dec 26 | vs Seahawks | 8:15 PM | 2-0 | 1.000 | Soldier Field · Chicago, IL |
Texans
Titans