| 3 | Sun Sep 22 | vs Dolphins | 4:05 PM | 1-1 | .500 | Lumen Field · Seattle, WA |
| 4 | Mon Sep 30 | at Lions | 8:15 PM | 1-1 | .500 | Ford Field · Detroit, MI |
| 5 | Sun Oct 6 | vs Giants | 4:25 PM | 0-2 | .000 | Lumen Field · Seattle, WA |
| 6 | Thu Oct 10 | vs 49ers | 8:15 PM | 1-1 | .500 | Lumen Field · Seattle, WA |
| 7 | Sun Oct 20 | at Falcons | 1:00 PM | 1-1 | .500 | Mercedes-Benz Stadium · Atlanta, GA |
| 8 | Sun Oct 27 | vs Bills | 4:05 PM | 2-0 | 1.000 | Lumen Field · Seattle, WA |
| 9 | Sun Nov 3 | vs Rams | 4:25 PM | 0-2 | .000 | Lumen Field · Seattle, WA |
| 11 | Sun Nov 17 | at49ers | 4:05 PM | 1-1 | .500 | Levi's® Stadium · Santa Clara, CA |
| 12 | Sun Nov 24 | vs Cardinals | 4:25 PM | 1-1 | .500 | Lumen Field · Seattle, WA |
| 13 | Sun Dec 1 | at Jets | 1:00 PM | 1-1 | .500 | MetLife Stadium · East Rutherford, NJ |
| 14 | Sun Dec 8 | atCardinals | 4:05 PM | 1-1 | .500 | State Farm Stadium · Glendale, AZ |
| 15 | Sun Dec 15 | vs Packers | 8:20 PM | 1-1 | .500 | Lumen Field · Seattle, WA |
| 16 | Sun Dec 22 | vs Vikings | 4:05 PM | 2-0 | 1.000 | Lumen Field · Seattle, WA |
| 17 | Thu Dec 26 | at Bears | 8:15 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 18 | TBD | atRams | TBD | 0-2 | .000 | SoFi Stadium · Inglewood, CA |
Patriots
Broncos