| 3 | Sun Sep 22 | at Raiders | 4:05 PM | 1-1 | .500 | Allegiant Stadium · Las Vegas, NV |
| 4 | Sun Sep 29 | vs Bengals | 1:00 PM | 0-2 | .000 | Bank of America Stadium · Charlotte, NC |
| 5 | Sun Oct 6 | at Bears | 1:00 PM | 1-1 | .500 | Soldier Field · Chicago, IL |
| 6 | Sun Oct 13 | vs Falcons | 4:25 PM | 1-1 | .500 | Bank of America Stadium · Charlotte, NC |
| 7 | Sun Oct 20 | at Commanders | 4:05 PM | 1-1 | .500 | FedEx Field · North Englewood, MD |
| 8 | Sun Oct 27 | at Broncos | 4:25 PM | 0-2 | .000 | Empower Field at Mile High · Denver, CO |
| 9 | Sun Nov 3 | vs Saints | 1:00 PM | 2-0 | 1.000 | Bank of America Stadium · Charlotte, NC |
| 10 | Sun Nov 10 | vs Giants | 9:30 AM | 0-2 | .000 | Bank of America Stadium · Charlotte, NC |
| 12 | Sun Nov 24 | vs Chiefs | 1:00 PM | 2-0 | 1.000 | Bank of America Stadium · Charlotte, NC |
| 13 | Sun Dec 1 | vs Buccaneers | 4:05 PM | 2-0 | 1.000 | Bank of America Stadium · Charlotte, NC |
| 14 | Sun Dec 8 | at Eagles | 1:00 PM | 1-1 | .500 | Lincoln Financial Field · Philadelphia, PA |
| 15 | Sun Dec 15 | vs Cowboys | 1:00 PM | 1-1 | .500 | Bank of America Stadium · Charlotte, NC |
| 16 | Sun Dec 22 | vs Cardinals | 1:00 PM | 1-1 | .500 | Bank of America Stadium · Charlotte, NC |
| 17 | Sun Dec 29 | atBuccaneers | 1:00 PM | 2-0 | 1.000 | Raymond James Stadium · Tampa, FL |
| 18 | TBD | atFalcons | TBD | 1-1 | .500 | Mercedes-Benz Stadium · Atlanta, GA |
Chargers