| 1 | Sun Sep 13 | vs Bears | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 2 | Sun Sep 20 | atFalcons | 1:00 PM | 0-0 | .000 | Mercedes-Benz Stadium · Atlanta, GA |
| 3 | Sun Sep 27 | atBrowns | 1:00 PM | 0-0 | .000 | FirstEnergy Stadium · Cleveland, OH |
| 4 | Sun Oct 4 | vsLions | 8:20 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| --bye week-- |
| 6 | Sun Oct 18 | atEagles | 1:00 PM | 0-0 | .000 | Lincoln Financial Field · Philadelphia, PA |
| 7 | Sun Oct 25 | vsBuccaneers | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 8 | Thu Oct 29 | atPackers | 8:15 PM | 0-0 | .000 | Lambeau Field · Green Bay, WI |
| 9 | Sun Nov 8 | vsBroncos | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 10 | Sun Nov 15 | atSaints | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 11 | Sun Nov 22 | vsRavens | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 12 | Mon Nov 30 | atBuccaneers | 8:15 PM | 0-0 | .000 | Raymond James Stadium · Tampa, FL |
| 13 | Sun Dec 6 | atVikings | 4:25 PM | 0-0 | .000 | U.S. Bank Stadium · Minneapolis, MN |
| 14 | Sun Dec 13 | vsSaints | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 15 | Sun Dec 20 | vsBengals | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 16 | TBD | atSteelers | TBD | 0-0 | .000 | Acrisure Stadium · Pittsburgh, PA |
| 17 | Sun Jan 3 | vsSeahawks | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 18 | TBD | vsFalcons | TBD | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
