| 1 | Sun Sep 13 | at Lions | 1:00 PM | 0-0 | .000 | Ford Field · Detroit, MI |
| 2 | Sun Sep 20 | atRavens | 1:00 PM | 0-0 | .000 | M&T Bank Stadium · Baltimore, MD |
| 3 | Sun Sep 27 | vsRaiders | 4:25 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 4 | Mon Oct 5 | vsFalcons | 8:15 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 5 | Sun Oct 11 | vsVikings | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 6 | Sun Oct 18 | atGiants | 1:00 PM | 0-0 | .000 | MetLife Stadium · East Rutherford, NJ |
| 7 | Sun Oct 25 | vsSteelers | 9:30 AM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| --bye week-- |
| 9 | Sun Nov 8 | vsBrowns | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 10 | Sun Nov 15 | vsPanthers | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 11 | Sun Nov 22 | atBears | 1:00 PM | 0-0 | .000 | Soldier Field · Chicago, IL |
| 12 | Sun Nov 29 | atBengals | 1:00 PM | 0-0 | .000 | Paycor Stadium · Cincinnati, OH |
| 13 | Sun Dec 6 | vsPackers | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 14 | Sun Dec 13 | atPanthers | 1:00 PM | 0-0 | .000 | Bank of America Stadium · Charlotte, NC |
| 15 | Sun Dec 20 | atBuccaneers | 1:00 PM | 0-0 | .000 | Raymond James Stadium · Tampa, FL |
| 16 | Sun Dec 27 | vsCardinals | 1:00 PM | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
| 17 | Sun Jan 3 | atFalcons | 1:00 PM | 0-0 | .000 | Mercedes-Benz Stadium · Atlanta, GA |
| 18 | TBD | vsBuccaneers | TBD | 0-0 | .000 | Caesars Superdome · New Orleans, LA |
