| 3 | Sun Sep 22 | at Buccaneers | 1:00 PM | 2-0 | 1.000 | Raymond James Stadium · Tampa, FL |
| 4 | Sun Sep 29 | at Jets | 1:00 PM | 1-1 | .500 | MetLife Stadium · East Rutherford, NJ |
| 5 | Sun Oct 6 | vs Raiders | 4:05 PM | 1-1 | .500 | Empower Field at Mile High · Denver, CO |
| 6 | Sun Oct 13 | vs Chargers | 4:05 PM | 2-0 | 1.000 | Empower Field at Mile High · Denver, CO |
| 7 | Thu Oct 17 | at Saints | 8:15 PM | 2-0 | 1.000 | Caesars Superdome · New Orleans, LA |
| 8 | Sun Oct 27 | vs Panthers | 4:25 PM | 0-2 | .000 | Empower Field at Mile High · Denver, CO |
| 9 | Sun Nov 3 | at Ravens | 1:00 PM | 0-2 | .000 | M&T Bank Stadium · Baltimore, MD |
| 10 | Sun Nov 10 | at Chiefs | 1:00 PM | 2-0 | 1.000 | Arrowhead Stadium · Kansas City, MO |
| 11 | Sun Nov 17 | vs Falcons | 4:05 PM | 1-1 | .500 | Empower Field at Mile High · Denver, CO |
| 12 | Sun Nov 24 | atRaiders | 4:05 PM | 1-1 | .500 | Allegiant Stadium · Las Vegas, NV |
| 13 | Mon Dec 2 | vs Browns | 8:15 PM | 1-1 | .500 | Empower Field at Mile High · Denver, CO |
| 15 | Sun Dec 15 | vs Colts | 4:25 PM | 0-2 | .000 | Empower Field at Mile High · Denver, CO |
| 16 | Sun Dec 22 | atChargers | 4:05 PM | 2-0 | 1.000 | SoFi Stadium · Inglewood, CA |
| 17 | TBD | at Bengals | TBD | 0-2 | .000 | Paycor Stadium · Cincinnati, OH |
| 18 | TBD | vsChiefs | TBD | 2-0 | 1.000 | Empower Field at Mile High · Denver, CO |
Steelers
Seahawks